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RPUSD2 RNA pseudouridine synthase domain containing 2 [ Homo sapiens (human) ]

Gene ID: 27079, updated on 13-Mar-2020

Summary

Official Symbol
RPUSD2provided by HGNC
Official Full Name
RNA pseudouridine synthase domain containing 2provided by HGNC
Primary source
HGNC:HGNC:24180
See related
Ensembl:ENSG00000166133
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PUS9; C18B11; C15orf19
Expression
Ubiquitous expression in lymph node (RPKM 2.9), testis (RPKM 2.6) and 25 other tissues See more
Orthologs

Genomic context

See RPUSD2 in Genome Data Viewer
Location:
15q15.1
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (40569293..40574949)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (40861503..40866666)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene RNA, U6 small nuclear 516, pseudogene Neighboring gene mitochondrial ribosomal protein L42 pseudogene 5 Neighboring gene coiled-coil domain containing 32 Neighboring gene tRNA-Ser (anticodon GCT) 4-2 Neighboring gene kinetochore scaffold 1 Neighboring gene RNA, 7SL, cytoplasmic 376, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ31409

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
pseudouridine synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
enzyme-directed rRNA pseudouridine synthesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
RNA pseudouridylate synthase domain-containing protein 2
Names
C18B11 homolog (44.9kD)
RNA pseudouridylate synthase domain containing 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001286407.1NP_001273336.1  RNA pseudouridylate synthase domain-containing protein 2 isoform 2

    See identical proteins and their annotated locations for NP_001273336.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AK293145, BC016967, DA746074
    Consensus CDS
    CCDS66737.1
    UniProtKB/Swiss-Prot
    Q8IZ73
    Related
    ENSP00000453036.1, ENST00000559271.1
    Conserved Domains (1) summary
    cd02557
    Location:147330
    PseudoU_synth_ScRIB2; Pseudouridine synthases similar to Saccharomyces cerevisiae RIB2
  2. NM_152260.3NP_689473.1  RNA pseudouridylate synthase domain-containing protein 2 isoform 1

    See identical proteins and their annotated locations for NP_689473.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC091045, AK055971, BC016967, DA746074
    Consensus CDS
    CCDS10061.1
    UniProtKB/Swiss-Prot
    Q8IZ73
    Related
    ENSP00000323288.7, ENST00000315616.12
    Conserved Domains (1) summary
    cd02557
    Location:208391
    PseudoU_synth_ScRIB2; Pseudouridine synthases similar to Saccharomyces cerevisiae RIB2

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    40569293..40574949
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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