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Bpifc BPI fold containing family C [ Mus musculus (house mouse) ]

Gene ID: 270757, updated on 8-Nov-2022

Summary

Official Symbol
Bpifcprovided by MGI
Official Full Name
BPI fold containing family Cprovided by MGI
Primary source
MGI:MGI:3026884
See related
Ensembl:ENSMUSG00000050108 AllianceGenome:MGI:3026884
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Bpil2; 4732454E24
Summary
Predicted to enable lipid binding activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human BPIFC (BPI fold containing family C). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in stomach adult (RPKM 1.7), limb E14.5 (RPKM 1.0) and 6 other tissues See more
Orthologs
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Genomic context

See Bpifc in Genome Data Viewer
Location:
10; 10 C1
Exon count:
16
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (85795555..85847724, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (85959691..86011860, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene achaete-scute family bHLH transcription factor 4 Neighboring gene predicted gene, 48175 Neighboring gene RNA 2',3'-cyclic phosphate and 5'-OH ligase Neighboring gene F-box protein 7 Neighboring gene predicted gene, 24430 Neighboring gene predicted gene, 51812 Neighboring gene synapsin III

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Markers

Homology

Clone Names

  • MGC130596

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
acts_upstream_of_or_within immune system process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within innate immune response IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
BPI fold-containing family C protein
Names
bactericidal/permeability-increasing protein-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177772.4NP_808440.2  BPI fold-containing family C protein precursor

    See identical proteins and their annotated locations for NP_808440.2

    Status: VALIDATED

    Source sequence(s)
    AK028764, BB527461, BC112376, BY142313
    Consensus CDS
    CCDS48658.1
    UniProtKB/Swiss-Prot
    Q8C186
    UniProtKB/TrEMBL
    Q3V1D7
    Related
    ENSMUSP00000063107.6, ENSMUST00000061699.12
    Conserved Domains (2) summary
    pfam01273
    Location:38202
    LBP_BPI_CETP; LBP / BPI / CETP family, N-terminal domain
    cl00188
    Location:242478
    BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    85795555..85847724 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)