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ATP2C1 ATPase secretory pathway Ca2+ transporting 1 [ Homo sapiens (human) ]

Gene ID: 27032, updated on 11-Sep-2019

Summary

Official Symbol
ATP2C1provided by HGNC
Official Full Name
ATPase secretory pathway Ca2+ transporting 1provided by HGNC
Primary source
HGNC:HGNC:13211
See related
Ensembl:ENSG00000017260 MIM:604384
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HHD; BCPM; PMR1; SPCA1; hSPCA1; ATP2C1A
Summary
The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Expression
Ubiquitous expression in prostate (RPKM 37.4), brain (RPKM 22.8) and 25 other tissues See more
Orthologs

Genomic context

See ATP2C1 in Genome Data Viewer
Location:
3q22.1
Exon count:
31
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (130850500..131016712)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (130569327..130735556)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986023 Neighboring gene uncharacterized LOC105374107 Neighboring gene uncharacterized LOC105374108 Neighboring gene glutathione S-transferase omega 3, pseudogene Neighboring gene cysteine and glycine rich protein 2 pseudogene Neighboring gene makorin ring finger protein 1 pseudogene Neighboring gene uncharacterized LOC107986024 Neighboring gene asteroid homolog 1 Neighboring gene NIMA related kinase 11 Neighboring gene RNA, U6 small nuclear 726, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1347

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
calcium-transporting ATPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
calcium-transporting ATPase activity IDA
Inferred from Direct Assay
more info
PubMed 
calcium-transporting ATPase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
manganese-transporting ATPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
proton-exporting ATPase activity, phosphorylative mechanism IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
Golgi calcium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Golgi calcium ion transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
actin cytoskeleton reorganization IMP
Inferred from Mutant Phenotype
more info
PubMed 
calcium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
calcium ion transport IDA
Inferred from Direct Assay
more info
PubMed 
calcium ion transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular calcium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular calcium ion homeostasis IDA
Inferred from Direct Assay
more info
PubMed 
cellular calcium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
epidermis development IMP
Inferred from Mutant Phenotype
more info
PubMed 
ion transmembrane transport TAS
Traceable Author Statement
more info
 
manganese ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
positive regulation of I-kappaB kinase/NF-kappaB signaling HMP PubMed 
proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Golgi membrane IDA
Inferred from Direct Assay
more info
PubMed 
Golgi membrane TAS
Traceable Author Statement
more info
 
integral component of membrane NAS
Non-traceable Author Statement
more info
PubMed 
membrane HDA PubMed 
trans-Golgi network IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
calcium-transporting ATPase type 2C member 1
Names
ATP-dependent Ca(2+) pump PMR1
ATPase 2C1
ATPase, Ca(2+)-sequestering
ATPase, Ca++ transporting, type 2C, member 1
HUSSY-28
secretory pathway Ca2+/Mn2+ ATPase 1
NP_001001485.1
NP_001001486.1
NP_001001487.1
NP_001186108.1
NP_001186109.1
NP_001186110.1
NP_001186111.1
NP_001186112.1
NP_001186113.1
NP_001186114.1
NP_055197.2
XP_005247411.1
XP_005247412.1
XP_005247413.1
XP_005247415.1
XP_011510988.1
XP_016861653.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_007379.2 RefSeqGene

    Range
    49066..171188
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001001485.2NP_001001485.1  calcium-transporting ATPase type 2C member 1 isoform 1c

    See identical proteins and their annotated locations for NP_001001485.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) has an alternate 5' sequence and lacks an internal exon in the 3' region, as compared to variant 6. The resulting isoform (1c) has shorter and distinct N- and C-termini, as compared to isoform 2a. Variants 3 and 11 encode the same isoform 1c.
    Source sequence(s)
    AF225981, BC028139, DA405579
    Consensus CDS
    CCDS46913.1
    UniProtKB/Swiss-Prot
    P98194
    Related
    ENSP00000432956.3, ENST00000533801.6
    Conserved Domains (6) summary
    TIGR01522
    Location:23878
    ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
    COG4087
    Location:556679
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:106339
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:726880
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:2694
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam13246
    Location:410493
    Cation_ATPase; Cation transport ATPase (P-type)
  2. NM_001001486.1NP_001001486.1  calcium-transporting ATPase type 2C member 1 isoform 1d

    See identical proteins and their annotated locations for NP_001001486.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) has an alternate 5' exon and an alternate splice site in the last splice junction, as compared to variant 6. The resulting isoform (1d) has a shorter and distinct N-terminus and an additional segment in the C-terminal region, as compared to isoform 2a.
    Source sequence(s)
    AF225981, AY268375, BC028139
    Consensus CDS
    CCDS33856.1
    UniProtKB/Swiss-Prot
    P98194
    Related
    ENSP00000352665.3, ENST00000359644.7
    Conserved Domains (6) summary
    TIGR01522
    Location:23903
    ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
    COG4087
    Location:556679
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:106339
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:726898
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:2694
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam13246
    Location:410493
    Cation_ATPase; Cation transport ATPase (P-type)
  3. NM_001001487.1NP_001001487.1  calcium-transporting ATPase type 2C member 1 isoform 1b

    See identical proteins and their annotated locations for NP_001001487.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) has an alternate 5' exon, as compared to variant 6. The resulting isoform (1b) has a shorter and distinct N-terminus, as compared to isoform 2a.
    Source sequence(s)
    AF225981, AY268375, BC028139
    Consensus CDS
    CCDS46912.1
    UniProtKB/Swiss-Prot
    P98194
    Related
    ENSP00000402677.2, ENST00000422190.6
    Conserved Domains (6) summary
    TIGR01522
    Location:23903
    ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
    COG4087
    Location:556679
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:106339
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:726898
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:2694
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam13246
    Location:410493
    Cation_ATPase; Cation transport ATPase (P-type)
  4. NM_001199179.2NP_001186108.1  calcium-transporting ATPase type 2C member 1 isoform 1a

    See identical proteins and their annotated locations for NP_001186108.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) has an alternate 5' sequence, lacks the 3' exon and contains an alternate 3' segment, as compared to variant 6. The resulting isoform (1a) has shorter and distinct N- and C-termini, as compared to isoform 2a. Variants 1 and 5 encode the same isoform 1a.
    Source sequence(s)
    AB037768, AC055733, BQ220831
    Consensus CDS
    CCDS46914.1
    UniProtKB/Swiss-Prot
    P98194
    Related
    ENSP00000424783.1, ENST00000508532.5
    Conserved Domains (6) summary
    TIGR01522
    Location:23903
    ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
    COG4087
    Location:556679
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:106339
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:726898
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:2694
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam13246
    Location:410493
    Cation_ATPase; Cation transport ATPase (P-type)
  5. NM_001199180.2NP_001186109.1  calcium-transporting ATPase type 2C member 1 isoform 2a

    See identical proteins and their annotated locations for NP_001186109.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) encodes the longest isoform (2a).
    Source sequence(s)
    AF225981, AK296470, DC422788
    Consensus CDS
    CCDS56278.1
    UniProtKB/Swiss-Prot
    P98194
    Related
    ENSP00000421326.3, ENST00000507488.6
    Conserved Domains (6) summary
    TIGR01522
    Location:57937
    ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
    COG4087
    Location:590713
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:140373
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:760932
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:60128
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam13246
    Location:444527
    Cation_ATPase; Cation transport ATPase (P-type)
  6. NM_001199181.2NP_001186110.1  calcium-transporting ATPase type 2C member 1 isoform 2b

    See identical proteins and their annotated locations for NP_001186110.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) lacks the 3' exon and contains an alternate 3' segment, as compared to variant 6. The resulting isoform (2b) has a shorter and distinct C-terminus, as compared to isoform 2a.
    Source sequence(s)
    AB037768, AK304374, BF669202, BF675663, BQ220831, DC422788
    Consensus CDS
    CCDS75006.1
    UniProtKB/Swiss-Prot
    P98194
    UniProtKB/TrEMBL
    B4E2Q0
    Related
    ENSP00000423774.2, ENST00000505330.5
    Conserved Domains (6) summary
    TIGR01522
    Location:57937
    ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
    COG4087
    Location:590713
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:140373
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:760932
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:60128
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam13246
    Location:444527
    Cation_ATPase; Cation transport ATPase (P-type)
  7. NM_001199182.2NP_001186111.1  calcium-transporting ATPase type 2C member 1 isoform 2c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) lacks an in-frame exon in the 5' CDS and has an alternate splice site in the last splice junction, as compared to variant 6. The resulting isoform (2c) lacks a segment in the N-terminal region and has an additional segment in the C-terminal region, as compared to isoform 2a.
    Source sequence(s)
    AF225981, AK299945, AY268375, DC422788
    Consensus CDS
    CCDS56279.1
    UniProtKB/Swiss-Prot
    P98194
    Related
    ENSP00000425320.2, ENST00000504381.5
    Conserved Domains (6) summary
    TIGR01522
    Location:57898
    ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
    COG4087
    Location:551674
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:101334
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:721893
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:1389
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam13246
    Location:405488
    Cation_ATPase; Cation transport ATPase (P-type)
  8. NM_001199183.2NP_001186112.1  calcium-transporting ATPase type 2C member 1 isoform 1e

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) has an alternate 5' exon, resulting in a downstream AUG start codon, as compared to variant 6. The resulting isoform (1e) is shorter at the N-terminus, as compared to isoform 2a.
    Source sequence(s)
    AF225981, AK304175, DC345627
    Consensus CDS
    CCDS56280.1
    UniProtKB/Swiss-Prot
    P98194
    UniProtKB/TrEMBL
    B4E295
    Related
    ENSP00000422872.1, ENST00000513801.5
    Conserved Domains (6) summary
    TIGR01522
    Location:7887
    ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
    COG4087
    Location:540663
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:90323
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:710882
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:1078
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam13246
    Location:394477
    Cation_ATPase; Cation transport ATPase (P-type)
  9. NM_001199184.2NP_001186113.1  calcium-transporting ATPase type 2C member 1 isoform 1f

    See identical proteins and their annotated locations for NP_001186113.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) has an alternate 5' exon, resulting in a downstream AUG start codon, lacks the 3' exon and contains an alternate 3' segment, as compared to variant 6. The resulting isoform (1f) is shorter at the N-terminus and has a shorter and distinct C-terminus, as compared to isoform 2a.
    Source sequence(s)
    AC055733, AF189723, BQ220831, DC345627
    Consensus CDS
    CCDS56281.1
    UniProtKB/Swiss-Prot
    P98194
    Related
    ENSP00000423330.1, ENST00000504948.5
    Conserved Domains (6) summary
    TIGR01522
    Location:7887
    ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
    COG4087
    Location:540663
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:90323
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:710882
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:1078
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam13246
    Location:394477
    Cation_ATPase; Cation transport ATPase (P-type)
  10. NM_001199185.2NP_001186114.1  calcium-transporting ATPase type 2C member 1 isoform 1c

    See identical proteins and their annotated locations for NP_001186114.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11) has an alternate 5' exon and lacks an internal exon in the 3' region, as compared to variant 6. The resulting isoform (1c) has shorter and distinct N- and C-termini, as compared to isoform 2a. Variants 3 and 11 encode the same isoform 1c.
    Source sequence(s)
    AF181121, AF225981, BC028139
    Consensus CDS
    CCDS46913.1
    UniProtKB/Swiss-Prot
    P98194
    Related
    ENSP00000329664.8, ENST00000328560.12
    Conserved Domains (6) summary
    TIGR01522
    Location:23878
    ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
    COG4087
    Location:556679
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:106339
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:726880
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:2694
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam13246
    Location:410493
    Cation_ATPase; Cation transport ATPase (P-type)
  11. NM_014382.4NP_055197.2  calcium-transporting ATPase type 2C member 1 isoform 1a

    See identical proteins and their annotated locations for NP_055197.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) has an alternate 5' exon, lacks the 3' exon and contains an alternate 3' segment, as compared to variant 6. The resulting isoform (1a) has shorter and distinct N- and C-termini, as compared to isoform 2a. Variants 1 and 5 encode the same isoform 1a.
    Source sequence(s)
    AC055733, AF181120, AK314342, BQ220831, DC343471
    Consensus CDS
    CCDS46914.1
    UniProtKB/Swiss-Prot
    P98194
    Related
    ENSP00000395809.2, ENST00000428331.6
    Conserved Domains (6) summary
    TIGR01522
    Location:23903
    ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
    COG4087
    Location:556679
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:106339
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:726898
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:2694
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam13246
    Location:410493
    Cation_ATPase; Cation transport ATPase (P-type)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    130850500..131016712
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005247354.2XP_005247411.1  calcium-transporting ATPase type 2C member 1 isoform X1

    Conserved Domains (6) summary
    TIGR01522
    Location:57937
    ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
    COG4087
    Location:590713
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:140373
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:760932
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:60128
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam13246
    Location:444527
    Cation_ATPase; Cation transport ATPase (P-type)
  2. XM_005247355.2XP_005247412.1  calcium-transporting ATPase type 2C member 1 isoform X2

    See identical proteins and their annotated locations for XP_005247412.1

    UniProtKB/Swiss-Prot
    P98194
    Conserved Domains (6) summary
    TIGR01522
    Location:23903
    ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
    COG4087
    Location:556679
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:106339
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:726898
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:2694
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam13246
    Location:410493
    Cation_ATPase; Cation transport ATPase (P-type)
  3. XM_005247356.3XP_005247413.1  calcium-transporting ATPase type 2C member 1 isoform X2

    See identical proteins and their annotated locations for XP_005247413.1

    UniProtKB/Swiss-Prot
    P98194
    Conserved Domains (6) summary
    TIGR01522
    Location:23903
    ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
    COG4087
    Location:556679
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:106339
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:726898
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:2694
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam13246
    Location:410493
    Cation_ATPase; Cation transport ATPase (P-type)
  4. XM_017006164.2XP_016861653.1  calcium-transporting ATPase type 2C member 1 isoform X3

    UniProtKB/Swiss-Prot
    P98194
    Conserved Domains (6) summary
    TIGR01522
    Location:23903
    ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
    COG4087
    Location:556679
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:106339
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:726898
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:2694
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam13246
    Location:410493
    Cation_ATPase; Cation transport ATPase (P-type)
  5. XM_005247358.3XP_005247415.1  calcium-transporting ATPase type 2C member 1 isoform X4

    Related
    ENSP00000425228.1, ENST00000504612.5
    Conserved Domains (6) summary
    TIGR01522
    Location:7887
    ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
    COG4087
    Location:540663
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:90323
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:710882
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:1078
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam13246
    Location:394477
    Cation_ATPase; Cation transport ATPase (P-type)
  6. XM_011512686.2XP_011510988.1  calcium-transporting ATPase type 2C member 1 isoform X5

    Conserved Domains (4) summary
    COG4087
    Location:278401
    COG4087; Soluble P-type ATPase [General function prediction only]
    pfam00122
    Location:2361
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:448620
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam13246
    Location:132215
    Cation_ATPase; Cation transport ATPase (P-type)
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