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Rnft2 ring finger protein, transmembrane 2 [ Mus musculus (house mouse) ]

Gene ID: 269695, updated on 12-Aug-2019

Summary

Official Symbol
Rnft2provided by MGI
Official Full Name
ring finger protein, transmembrane 2provided by MGI
Primary source
MGI:MGI:2442859
See related
Ensembl:ENSMUSG00000032850
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tmem118; AW049082; B830028P19Rik
Expression
Biased expression in whole brain E14.5 (RPKM 9.2), CNS E14 (RPKM 9.0) and 14 other tissues See more
Orthologs

Genomic context

See Rnft2 in Genome Data Viewer
Location:
5; 5 F
Exon count:
15
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (118190734..118245510, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (118640745..118695034, complement)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 30522 Neighboring gene harakiri, BCL2 interacting protein (contains only BH3 domain) Neighboring gene RIKEN cDNA 2410131K14 gene Neighboring gene predicted gene, 25076 Neighboring gene predicted gene, 46942

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
RING finger and transmembrane domain-containing protein 2
Names
transmembrane protein 118

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109902.1NP_001103372.1  RING finger and transmembrane domain-containing protein 2 isoform 2

    See identical proteins and their annotated locations for NP_001103372.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and at a single splice boundary, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    AW049082, BC057302, BY721494
    Consensus CDS
    CCDS51632.1
    UniProtKB/Swiss-Prot
    Q3UF64
    Related
    ENSMUSP00000113749.1, ENSMUST00000121369.7
    Conserved Domains (1) summary
    cd00162
    Location:385425
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
  2. NM_172998.3NP_766586.2  RING finger and transmembrane domain-containing protein 2 isoform 1

    See identical proteins and their annotated locations for NP_766586.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK046850, AW049082, BU611972
    Consensus CDS
    CCDS19611.2
    UniProtKB/Swiss-Prot
    Q3UF64
    Related
    ENSMUSP00000112903.1, ENSMUST00000117177.7
    Conserved Domains (1) summary
    cd00162
    Location:386426
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p6 C57BL/6J

    Range
    118190734..118245510 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006530344.2XP_006530407.1  RING finger and transmembrane domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006530407.1

    UniProtKB/Swiss-Prot
    Q3UF64
    Conserved Domains (1) summary
    cd00162
    Location:386426
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
  2. XM_006530349.2XP_006530412.1  RING finger and transmembrane domain-containing protein 2 isoform X2

    See identical proteins and their annotated locations for XP_006530412.1

    UniProtKB/Swiss-Prot
    Q3UF64
    Conserved Domains (1) summary
    cd00162
    Location:385425
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
  3. XM_006530348.2XP_006530411.1  RING finger and transmembrane domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006530411.1

    UniProtKB/Swiss-Prot
    Q3UF64
    Conserved Domains (1) summary
    cd00162
    Location:386426
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
  4. XM_030254537.1XP_030110397.1  RING finger and transmembrane domain-containing protein 2 isoform X2

  5. XM_006530345.2XP_006530408.1  RING finger and transmembrane domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006530408.1

    UniProtKB/Swiss-Prot
    Q3UF64
    Conserved Domains (1) summary
    cd00162
    Location:386426
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
  6. XM_017320901.1XP_017176390.1  RING finger and transmembrane domain-containing protein 2 isoform X2

    UniProtKB/Swiss-Prot
    Q3UF64
    Conserved Domains (1) summary
    cd00162
    Location:385425
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
  7. XM_006530347.2XP_006530410.1  RING finger and transmembrane domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006530410.1

    UniProtKB/Swiss-Prot
    Q3UF64
    Conserved Domains (1) summary
    cd00162
    Location:386426
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
  8. XM_006530346.4XP_006530409.1  RING finger and transmembrane domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006530409.1

    UniProtKB/Swiss-Prot
    Q3UF64
    Conserved Domains (1) summary
    cd00162
    Location:386426
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
  9. XM_006530350.2XP_006530413.1  RING finger and transmembrane domain-containing protein 2 isoform X3

    Conserved Domains (1) summary
    cl17238
    Location:385402
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
  10. XM_030254539.1XP_030110399.1  RING finger and transmembrane domain-containing protein 2 isoform X5

  11. XM_030254538.1XP_030110398.1  RING finger and transmembrane domain-containing protein 2 isoform X4

    Related
    ENSMUSP00000120260.1, ENSMUST00000154786.7
  12. XM_030254540.1XP_030110400.1  RING finger and transmembrane domain-containing protein 2 isoform X5

RNA

  1. XR_878686.2 RNA Sequence

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