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Cops7b COP9 signalosome subunit 7B [ Mus musculus (house mouse) ]

Gene ID: 26895, updated on 5-Aug-2018
Official Symbol
Cops7bprovided by MGI
Official Full Name
COP9 signalosome subunit 7Bprovided by MGI
Primary source
MGI:MGI:1349388
See related
Ensembl:ENSMUSG00000026240 Vega:OTTMUSG00000027307
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D1Wsu66e; E130114M23
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 20.7), CNS E14 (RPKM 19.9) and 28 other tissues See more
Orthologs
See Cops7b in Genome Data Viewer
Location:
1 C5; 1 43.97 cM
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (86582892..86606500)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (88483675..88503075)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene prothymosin alpha Neighboring gene phosphodiesterase 6D, cGMP-specific, rod, delta Neighboring gene predicted gene, 41908 Neighboring gene natriuretic peptide type C

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
protein deneddylation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
COP9 signalosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
COP9 signalosome ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
COP9 signalosome complex subunit 7b
Names
COP9 (constitutive photomorphogenic) homolog, subunit 7b
COP9 complex S7b
JAB1-containing signalosome subunit 7b
SGN7b
signalosome subunit 7b

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360887.1NP_001347816.1  COP9 signalosome complex subunit 7b isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AC158132
    Conserved Domains (1) summary
    smart00088
    Location:88177
    PINT; motif in proteasome subunits, Int-6, Nip-1 and TRIP-15
  2. NM_001360888.1NP_001347817.1  COP9 signalosome complex subunit 7b isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate exon compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a.
    Source sequence(s)
    AC158132, AK053615
    Conserved Domains (1) summary
    smart00088
    Location:656
    PINT; motif in proteasome subunits, Int-6, Nip-1 and TRIP-15
  3. NM_172974.3NP_766562.1  COP9 signalosome complex subunit 7b isoform a

    See identical proteins and their annotated locations for NP_766562.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AC158132, AI121193, AK081309, CN721267
    Consensus CDS
    CCDS15122.1
    UniProtKB/Swiss-Prot
    Q8BV13
    Related
    ENSMUSP00000027446.4, ENSMUST00000027446.10
    Conserved Domains (1) summary
    smart00088
    Location:88177
    PINT; motif in proteasome subunits, Int-6, Nip-1 and TRIP-15

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

    Range
    86582892..86606500
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006529625.3XP_006529688.1  COP9 signalosome complex subunit 7b isoform X2

    Conserved Domains (1) summary
    smart00753
    Location:76165
    PAM; PCI/PINT associated module
  2. XM_006529623.3XP_006529686.1  COP9 signalosome complex subunit 7b isoform X1

    UniProtKB/Swiss-Prot
    Q8BV13
    Related
    ENSMUSP00000113587.1, OTTMUSP00000033969, ENSMUST00000121534.7, OTTMUST00000067485
    Conserved Domains (1) summary
    smart00088
    Location:88177
    PINT; motif in proteasome subunits, Int-6, Nip-1 and TRIP-15
  3. XM_006529624.3XP_006529687.1  COP9 signalosome complex subunit 7b isoform X1

    UniProtKB/Swiss-Prot
    Q8BV13
    Conserved Domains (1) summary
    smart00088
    Location:88177
    PINT; motif in proteasome subunits, Int-6, Nip-1 and TRIP-15
  4. XM_011248010.2XP_011246312.1  COP9 signalosome complex subunit 7b isoform X3

    Conserved Domains (1) summary
    smart00088
    Location:656
    PINT; motif in proteasome subunits, Int-6, Nip-1 and TRIP-15
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