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Slc38a9 solute carrier family 38, member 9 [ Mus musculus (house mouse) ]

Gene ID: 268706, updated on 27-Nov-2024

Summary

Official Symbol
Slc38a9provided by MGI
Official Full Name
solute carrier family 38, member 9provided by MGI
Primary source
MGI:MGI:1918839
See related
Ensembl:ENSMUSG00000047789 AllianceGenome:MGI:1918839
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A730092C09; 4833412L08Rik; 6720411P22Rik; 9130023D20Rik; 9430067K09Rik
Summary
Predicted to enable several functions, including L-amino acid transmembrane transporter activity; arginine binding activity; and cholesterol binding activity. Predicted to be involved in carboxylic acid transport; cellular response to amino acid stimulus; and positive regulation of TORC1 signaling. Predicted to be located in late endosome and lysosome. Predicted to be part of FNIP-folliculin RagC/D GAP and Ragulator complex. Predicted to be active in lysosomal membrane. Orthologous to human SLC38A9 (solute carrier family 38 member 9). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in testis adult (RPKM 7.7), thymus adult (RPKM 4.8) and 26 other tissues See more
Orthologs
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Genomic context

See Slc38a9 in Genome Data Viewer
Location:
13 D2.2; 13 63.93 cM
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (112792723..112875286)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (112656189..112738752)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene tubulin, alpha 1B pseudogene Neighboring gene STARR-seq mESC enhancer starr_35695 Neighboring gene DEAD box helicase 4 Neighboring gene STARR-positive B cell enhancer ABC_E10817 Neighboring gene STARR-positive B cell enhancer ABC_E10818 Neighboring gene STARR-positive B cell enhancer ABC_E9889 Neighboring gene STARR-positive B cell enhancer mm9_chr13:113485543-113485843 Neighboring gene heterogeneous nuclear ribonucleoprotein R pseudogene Neighboring gene STARR-seq mESC enhancer starr_35698 Neighboring gene STARR-seq mESC enhancer starr_35701 Neighboring gene predicted gene, 41067 Neighboring gene STARR-seq mESC enhancer starr_35702 Neighboring gene phospholipid phosphatase 1 Neighboring gene Mtr4 exosome RNA helicase

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4) 
  • Gene trapped (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables L-arginine transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables L-arginine transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables L-asparagine transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables L-asparagine transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables L-glutamine transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables L-glutamine transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables L-leucine transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables L-leucine transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables amino acid transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables amino acid transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables arginine binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables cholesterol binding ISO
Inferred from Sequence Orthology
more info
 
enables cholesterol binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables guanyl-nucleotide exchange factor activity ISO
Inferred from Sequence Orthology
more info
 
enables guanyl-nucleotide exchange factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables sterol sensor activity ISO
Inferred from Sequence Orthology
more info
 
enables sterol sensor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in L-arginine transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
involved_in L-arginine transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in amino acid transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
involved_in amino acid transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in asparagine transport ISO
Inferred from Sequence Orthology
more info
 
involved_in asparagine transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in branched-chain amino acid transport IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular response to amino acid stimulus ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to amino acid stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in glutamine transport ISO
Inferred from Sequence Orthology
more info
 
involved_in glutamine transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of TOR signaling ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of TOR signaling ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of TORC1 signaling ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of TORC1 signaling ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
part_of FNIP-folliculin RagC/D GAP IEA
Inferred from Electronic Annotation
more info
 
part_of FNIP-folliculin RagC/D GAP ISO
Inferred from Sequence Orthology
more info
 
part_of Ragulator complex ISO
Inferred from Sequence Orthology
more info
 
part_of Ragulator complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in late endosome ISO
Inferred from Sequence Orthology
more info
 
located_in late endosome ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in late endosome membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in lysosomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in lysosomal membrane ISO
Inferred from Sequence Orthology
more info
 
located_in lysosomal membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in lysosome ISO
Inferred from Sequence Orthology
more info
 
located_in lysosome ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
neutral amino acid transporter 9
Names
putative sodium-coupled neutral amino acid transporter 9
sodium-coupled neutral amino acid transporter 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178746.4NP_848861.1  neutral amino acid transporter 9

    See identical proteins and their annotated locations for NP_848861.1

    Status: VALIDATED

    Source sequence(s)
    AC159242, AK044735, BC052361
    Consensus CDS
    CCDS26775.1
    UniProtKB/Swiss-Prot
    Q80W70, Q8BGD6, Q8C5C3
    Related
    ENSMUSP00000052172.5, ENSMUST00000052514.6
    Conserved Domains (1) summary
    cl00456
    Location:114556
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    112792723..112875286
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030247276.1XP_030103136.1  neutral amino acid transporter 9 isoform X1

    UniProtKB/Swiss-Prot
    Q80W70, Q8BGD6, Q8C5C3
    Conserved Domains (1) summary
    cl00456
    Location:114556
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  2. XM_006517670.4XP_006517733.1  neutral amino acid transporter 9 isoform X1

    See identical proteins and their annotated locations for XP_006517733.1

    UniProtKB/Swiss-Prot
    Q80W70, Q8BGD6, Q8C5C3
    Conserved Domains (1) summary
    cl00456
    Location:114556
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  3. XM_006517671.5XP_006517734.1  neutral amino acid transporter 9 isoform X2

    See identical proteins and their annotated locations for XP_006517734.1

    Conserved Domains (1) summary
    cl00456
    Location:107549
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  4. XM_006517673.5XP_006517736.1  neutral amino acid transporter 9 isoform X3

    See identical proteins and their annotated locations for XP_006517736.1

    Conserved Domains (1) summary
    cl00456
    Location:52494
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  5. XM_017315519.3XP_017171008.1  neutral amino acid transporter 9 isoform X3

    Conserved Domains (1) summary
    cl00456
    Location:52494
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  6. XM_036158054.1XP_036013947.1  neutral amino acid transporter 9 isoform X4

    Conserved Domains (1) summary
    cl00456
    Location:37289
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  7. XM_006517672.3XP_006517735.1  neutral amino acid transporter 9 isoform X2

    See identical proteins and their annotated locations for XP_006517735.1

    Conserved Domains (1) summary
    cl00456
    Location:107549
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  8. XM_006517675.4XP_006517738.1  neutral amino acid transporter 9 isoform X3

    See identical proteins and their annotated locations for XP_006517738.1

    Conserved Domains (1) summary
    cl00456
    Location:52494
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

RNA

  1. XR_001780783.3 RNA Sequence

  2. XR_003950453.2 RNA Sequence

  3. XR_382737.5 RNA Sequence

  4. XR_873763.4 RNA Sequence

  5. XR_873764.4 RNA Sequence

  6. XR_873762.4 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_175376.2: Suppressed sequence

    Description
    NM_175376.2: This RefSeq was permanently suppressed because it is primarily UTR sequence.