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Rpl23a ribosomal protein L23A [ Mus musculus (house mouse) ]

Gene ID: 268449, updated on 8-Dec-2022

Summary

Official Symbol
Rpl23aprovided by MGI
Official Full Name
ribosomal protein L23Aprovided by MGI
Primary source
MGI:MGI:3040672
See related
Ensembl:ENSMUSG00000058546 AllianceGenome:MGI:3040672
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MDA20
Summary
Enables TORC2 complex binding activity. Predicted to be involved in ribosomal large subunit assembly. Predicted to be located in cytosolic ribosome and nucleus. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in brain. Orthologous to human RPL23A (ribosomal protein L23a). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 878.5), liver E14 (RPKM 813.0) and 23 other tissues See more
Orthologs
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Genomic context

See Rpl23a in Genome Data Viewer
Location:
11; 11 B5
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (78071761..78074410, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (78180935..78183584, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene NIMA (never in mitosis gene a)-related expressed kinase 8 Neighboring gene microRNA 7653 Neighboring gene TLC domain containing 1 Neighboring gene small nucleolar RNA, C/D box 42A Neighboring gene small nucleolar RNA, C/D box 4A Neighboring gene small nucleolar RNA, C/D box 42B Neighboring gene Rab34 Hedgehog-responsive enhancer Neighboring gene RAB34, member RAS oncogene family Neighboring gene protein interacting with cyclin A1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC36820, MGC107550, MGC107551

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables TORC2 complex binding IDA
Inferred from Direct Assay
more info
PubMed 
enables large ribosomal subunit rRNA binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
PubMed 
involved_in ribosomal large subunit assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translation at postsynapse NAS
Non-traceable Author Statement
more info
PubMed 
involved_in translation at presynapse NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm NAS
Non-traceable Author Statement
more info
PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
 
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of cytosolic large ribosomal subunit IPI
Inferred from Physical Interaction
more info
PubMed 
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
is_active_in postsynapse NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in presynapse NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in ribosome NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in synapse NAS
Non-traceable Author Statement
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207523.2NP_997406.1  60S ribosomal protein L23a

    See identical proteins and their annotated locations for NP_997406.1

    Status: VALIDATED

    Source sequence(s)
    BC125642, BY271596, BY585987
    Consensus CDS
    CCDS25093.1
    UniProtKB/Swiss-Prot
    P62751
    UniProtKB/TrEMBL
    A0A6P5QNR5, Q5M9M5
    Related
    ENSMUSP00000099541.5, ENSMUST00000102483.5
    Conserved Domains (1) summary
    PTZ00191
    Location:36156
    PTZ00191; 60S ribosomal protein L23a; Provisional

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    78071761..78074410 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)