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RNU4-2 RNA, U4 small nuclear 2 [ Homo sapiens (human) ]

Gene ID: 26834, updated on 9-Jun-2025
Official Symbol
RNU4-2provided by HGNC
Official Full Name
RNA, U4 small nuclear 2provided by HGNC
Primary source
HGNC:HGNC:10193
See related
Ensembl:ENSG00000202538 MIM:620823; AllianceGenome:HGNC:10193
Gene type
snRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
U4A; U4b; U4c; RENU; RNU4C; RNU4B1; NEDHAFA; RNU4-1B
Summary
Predicted to enable U6 snRNA binding activity. Predicted to be involved in formation of quadruple SL/U4/U5/U6 snRNP and spliceosomal tri-snRNP complex assembly. Predicted to be part of U4 snRNP and U4/U6 x U5 tri-snRNP complex. [provided by Alliance of Genome Resources, Jun 2025]
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Location:
12q24.23
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (120291759..120291903, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (120278937..120279081, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (120729562..120729706, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene paxillin Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7137 Neighboring gene ribosomal protein S20 pseudogene 31 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:120697989-120698555 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4945 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4946 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:120717966-120718466 Neighboring gene hESC enhancers GRCh37_chr12:120727716-120728708 and GRCh37_chr12:120728709-120729700 Neighboring gene NME2 pseudogene 1 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:120730693-120731684 Neighboring gene RNA, U4 small nuclear 1 Neighboring gene sirtuin 4 Neighboring gene RNA, U6 small nuclear 1088, pseudogene

Products Interactant Other Gene Complex Source Pubs Description

Markers

Other Names

  • RNA, U4 small nuclear 1B
  • RNA, U4B1 small nuclear
  • RNA, U4C small nuclear

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_003137.3 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC004263
    Related
    ENST00000365668.2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    120291759..120291903 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    120278937..120279081 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)