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GAGE12I G antigen 12I [ Homo sapiens (human) ]

Gene ID: 26748, updated on 30-Jul-2019

Summary

Official Symbol
GAGE12Iprovided by HGNC
Official Full Name
G antigen 12Iprovided by HGNC
Primary source
HGNC:HGNC:4105
See related
MIM:300637
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AL4; CT4.7; GAGE7B; GAGE-7B
Summary
This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YYWPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008]
Annotation information
Annotation category: suggests misassembly
not in current annotation release

Genomic context

See GAGE12I in Genome Data Viewer
Location:
Xp11.23
Annotation release Status Assembly Chr Location
105 latest, but not current GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (49216677..49223943)

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
G antigen 12I
Names
G antigen 12G
G antigen 7B
cancer/testis antigen 4.7
g antigen 12F/G/I

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001477.1NP_001468.1  G antigen 12I

    See identical proteins and their annotated locations for NP_001468.1

    Status: REVIEWED

    Source sequence(s)
    AF055474
    UniProtKB/Swiss-Prot
    O76087, P0CL80, P0CL81, P0CL82
    Conserved Domains (1) summary
    pfam05831
    Location:1111
    GAGE; GAGE protein
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