U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

OR2J2 olfactory receptor family 2 subfamily J member 2 [ Homo sapiens (human) ]

Gene ID: 26707, updated on 27-Nov-2024

Summary

Official Symbol
OR2J2provided by HGNC
Official Full Name
olfactory receptor family 2 subfamily J member 2provided by HGNC
Primary source
HGNC:HGNC:8260
See related
Ensembl:ENSG00000204700 AllianceGenome:HGNC:8260
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR6-8; OR6-19; ORL684; OR6.3.8; hs6M1-6; dJ80I19.4
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See OR2J2 in Genome Data Viewer
Location:
6p22.1
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (29170907..29175811)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (29045636..29050536)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (29138684..29143588)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily J member 3 Neighboring gene olfactory receptor family 2 subfamily N member 1 pseudogene Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr6:29127190-29128389 Neighboring gene olfactory receptor family 2 subfamily J member 4 pseudogene Neighboring gene uncharacterized LOC124901297

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

EBI GWAS Catalog

Description
Common variation contributes to the genetic architecture of social communication traits.
EBI GWAS Catalog

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC119134, MGC119135, MGC119136, MGC119137

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in detection of chemical stimulus involved in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 2J2
Names
olfactory receptor 6-8
olfactory receptor OR6-19

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030905.3NP_112167.2  olfactory receptor 2J2

    See identical proteins and their annotated locations for NP_112167.2

    Status: VALIDATED

    Source sequence(s)
    AL645937
    Consensus CDS
    CCDS43434.1
    UniProtKB/TrEMBL
    A0A126GVA5, A0A126GW07, A0A126GWS4
    Related
    ENSP00000493401.1, ENST00000641417.1
    Conserved Domains (1) summary
    cd15947
    Location:27295
    7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    29170907..29175811
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_167244.2 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    436533..441433
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

  1. NT_113891.3 Reference GRCh38.p14 ALT_REF_LOCI_2

    Range
    657450..662354
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_3

Genomic

  1. NT_167245.2 Reference GRCh38.p14 ALT_REF_LOCI_3

    Range
    436514..441414
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_4

Genomic

  1. NT_167246.2 Reference GRCh38.p14 ALT_REF_LOCI_4

    Range
    436470..441370
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_5

Genomic

  1. NT_167247.2 Reference GRCh38.p14 ALT_REF_LOCI_5

    Range
    436644..441548
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_6

Genomic

  1. NT_167248.2 Reference GRCh38.p14 ALT_REF_LOCI_6

    Range
    436497..441397
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_7

Genomic

  1. NT_167249.2 Reference GRCh38.p14 ALT_REF_LOCI_7

    Range
    480275..485175
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    29045636..29050536
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)