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OR4D1 olfactory receptor family 4 subfamily D member 1 [ Homo sapiens (human) ]

Gene ID: 26689, updated on 26-Oct-2022

Summary

Official Symbol
OR4D1provided by HGNC
Official Full Name
olfactory receptor family 4 subfamily D member 1provided by HGNC
Primary source
HGNC:HGNC:8293
See related
Ensembl:ENSG00000141194 AllianceGenome:HGNC:8293
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR4D3; OR4D4P; TPCR16; OR17-23
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR4D1 in Genome Data Viewer
Location:
17q22
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (58148384..58159585)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (59016289..59027481)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (56225745..56236946)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 5901 Neighboring gene dynein light chain LC8-type 2 Neighboring gene Sharpr-MPRA regulatory region 5260 Neighboring gene msh homeobox 2 pseudogene 1 Neighboring gene olfactory receptor family 4 subfamily D member 2 Neighboring gene eosinophil peroxidase

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables olfactory receptor activity NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in membrane NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
olfactory receptor 4D1
Names
olfactory receptor 4D3
olfactory receptor OR17-23 pseudogene
olfactory receptor TPCR16
olfactory receptor, family 4, subfamily D, member 3
olfactory receptor, family 4, subfamily D, member 4 pseudogene
seven transmembrane helix receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001386095.1NP_001373024.1  olfactory receptor 4D1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC005962
    Consensus CDS
    CCDS42365.1
    UniProtKB/Swiss-Prot
    Q96R76
    Related
    ENSP00000365451.3, ENST00000268912.6
    Conserved Domains (1) summary
    cd15936
    Location:34291
    7tmA_OR4D-like; olfactory receptor 4D and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. NM_012374.2NP_036506.1  olfactory receptor 4D1

    See identical proteins and their annotated locations for NP_036506.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC005962
    Consensus CDS
    CCDS42365.1
    UniProtKB/Swiss-Prot
    Q15615, Q96R76
    Related
    ENSP00000493234.1, ENST00000641449.1
    Conserved Domains (1) summary
    cd15936
    Location:34291
    7tmA_OR4D-like; olfactory receptor 4D and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    58148384..58159585
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    59016289..59027481
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)