Format

Send to:

Choose Destination

Tbkbp1 TBK1 binding protein 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 266764, updated on 25-Jan-2022

Summary

Official Symbol
Tbkbp1provided by RGD
Official Full Name
TBK1 binding protein 1provided by RGD
Primary source
RGD:631328
See related
Ensembl:ENSRNOG00000009370 AllianceGenome:RGD:631328
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Prosapip2
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in I-kappaB kinase/NF-kappaB signaling. Predicted to be active in cytoplasm. Orthologous to human TBKBP1 (TBK1 binding protein 1). [provided by Alliance of Genome Resources, Nov 2021]
Expression
Biased expression in Brain (RPKM 32.3), Lung (RPKM 31.1) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Tbkbp1 in Genome Data Viewer
Location:
10q31
Exon count:
11
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (82120558..82135749, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (85071058..85085596, complement)

Chromosome 10 - NC_051345.1Genomic Context describing neighboring genes Neighboring gene oxysterol binding protein-like 7 Neighboring gene T-box transcription factor 21 Neighboring gene karyopherin subunit beta 1 Neighboring gene aminopeptidase puromycin sensitive

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in I-kappaB kinase/NF-kappaB signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
TANK-binding kinase 1-binding protein 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172021.2NP_742018.2  TANK-binding kinase 1-binding protein 1

    See identical proteins and their annotated locations for NP_742018.2

    Status: PROVISIONAL

    Source sequence(s)
    BC076503
    UniProtKB/Swiss-Prot
    Q6DG50
    Related
    ENSRNOP00000012461.4, ENSRNOT00000012462.5
    Conserved Domains (2) summary
    TIGR02168
    Location:50333
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam12845
    Location:289342
    TBD; TBD domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051345.1 Reference mRatBN7.2 Primary Assembly

    Range
    82120558..82135749 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039085315.1XP_038941243.1  TANK-binding kinase 1-binding protein 1 isoform X1

    Conserved Domains (2) summary
    TIGR02168
    Location:50333
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam12845
    Location:289342
    TBD; TBD domain
  2. XM_039085316.1XP_038941244.1  TANK-binding kinase 1-binding protein 1 isoform X2

    Conserved Domains (2) summary
    TIGR02168
    Location:53340
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam12845
    Location:288341
    TBD; TBD domain
Support Center