Format

Send to:

Choose Destination

Ugt2b17 UDP glucuronosyltransferase 2 family, polypeptide B15 [ Rattus norvegicus (Norway rat) ]

Gene ID: 266685, updated on 21-Jul-2018

Summary

Official Symbol
Ugt2b17provided by RGD
Official Full Name
UDP glucuronosyltransferase 2 family, polypeptide B15provided by RGD
Primary source
RGD:628623
See related
Ensembl:ENSRNOG00000046540
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Udpgt; Rlug38; Ugt2b3; Ugt2b5; Udpgtr-3; UDPGT 2B5
Summary
enzyme which glucuronidates testosterone, dihydrotestosterone, and beta-estradiol [RGD, Feb 2006]
Expression
Restricted expression toward (RPKM 1090.9) See more

Genomic context

See Ugt2b17 in Genome Data Viewer
Location:
14p21
Exon count:
14
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (22375428..22486291)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 14 NC_005113.3 (22286423..22295392)

Chromosome 14 - NC_005113.4Genomic Context describing neighboring genes Neighboring gene similar to T-cell activation kelch repeat protein Neighboring gene hypothetical LOC100364155 Neighboring gene kelch repeat and BTB (POZ) domain containing 8-like Neighboring gene UDP-glucuronosyltransferase 2 family, member 37 Neighboring gene UDP glucuronosyltransferase 2 family, polypeptide B35

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
UDP-glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glucuronosyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
glucuronosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cellular response to ethanol IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to glucocorticoid stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to growth hormone stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to testosterone stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
response to lipopolysaccharide IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
organelle membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
UDP-glucuronosyltransferase 2B17
Names
17-beta-hydroxysteroid specific
17-beta-hydroxysteroid-specific UDPGT
UDP glucuronosyltransferase 2 family, polypeptide B17
UDP glucuronosyltransferase 2 family, polypeptide B5
UDP glycosyltransferase 2 family, member 3
UDP-glucuronosyltransferase 2B3 precursor, microsomal
UDP-glucuronosyltransferase 2B5
UDPGT 2B17
UDPGT 2B3
liver 17 beta-hydroxysteroid UDP-glucuronosyltransferase
testosterone, dihydrotestosterone, and beta-estradiol specific
testosterone, dihydrotestosterone, and beta-estradiol-specific UDPGT
NP_695226.2
XP_006250862.1
XP_008768219.1
XP_008768220.1
XP_008768222.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153314.2NP_695226.2  UDP-glucuronosyltransferase 2B17 precursor

    See identical proteins and their annotated locations for NP_695226.2

    Status: PROVISIONAL

    Source sequence(s)
    M31109
    UniProtKB/Swiss-Prot
    P08542
    Related
    ENSRNOP00000034723.6, ENSRNOT00000034784.6
    Conserved Domains (2) summary
    PHA03392
    Location:8489
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:24527
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005113.4 Reference Rnor_6.0 Primary Assembly

    Range
    22375428..22486291
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008769998.2XP_008768220.1  UDP-glucuronosyltransferase 2B17 isoform X1

    Conserved Domains (2) summary
    PHA03392
    Location:8489
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:24527
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
  2. XM_006250800.3XP_006250862.1  UDP-glucuronosyltransferase 2B17 isoform X3

    Conserved Domains (2) summary
    pfam00201
    Location:24337
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
    cl10013
    Location:45337
    Glycosyltransferase_GTB_type; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate ...
  3. XM_008769997.2XP_008768219.1  UDP-glucuronosyltransferase 2B17 isoform X2

    Related
    ENSRNOP00000043239.4, ENSRNOT00000052369.5
    Conserved Domains (2) summary
    PHA03392
    Location:1492
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:27530
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
  4. XM_008770000.2XP_008768222.1  UDP-glucuronosyltransferase 2B17 isoform X4

    Conserved Domains (2) summary
    PHA03392
    Location:1510
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:27523
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

Alternate Rn_Celera

Genomic

  1. AC_000082.1 Alternate Rn_Celera

    Range
    20276987..20292566
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center