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sec31a SEC31 homolog A, COPII coat complex component [ Danio rerio (zebrafish) ]

Gene ID: 266638, updated on 4-Nov-2022

Summary

Official Symbol
sec31aprovided by ZNC
Official Full Name
SEC31 homolog A, COPII coat complex componentprovided by ZNC
Primary source
ZFIN:ZDB-GENE-020919-2
See related
Ensembl:ENSDARG00000021082 AllianceGenome:ZFIN:ZDB-GENE-020919-2
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb354; sec31p; zgc:63547
Summary
Predicted to enable structural molecule activity. Acts upstream of or within digestive system development; endoplasmic reticulum organization; and liver development. Predicted to be located in COPII-coated ER to Golgi transport vesicle. Predicted to be part of COPII vesicle coat. Predicted to be active in endoplasmic reticulum exit site. Is expressed in several structures, including alar plate midbrain region; axis; digestive system; fin; and midbrain. Orthologous to human SEC31A (SEC31 homolog A, COPII coat complex component). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See sec31a in Genome Data Viewer
Location:
chromosome: 10
Exon count:
29
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (5092500..5135788, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (5092169..5135484, complement)
103 previous assembly Zv9 (GCF_000002035.4) 10 NC_007121.5 (5097530..5139190, complement)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 150C Neighboring gene coactivator-associated arginine methyltransferase 1, like Neighboring gene zgc:113274 Neighboring gene uncharacterized LOC110438839

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables structural molecule activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of COPII vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of COPII vesicle coat ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in COPII-coated ER to Golgi transport vesicle ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum exit site IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum exit site ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein transport protein Sec31A
Names
SEC31-like protein 1
SEC31-related protein A
sec31p homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199530.2NP_955824.2  protein transport protein Sec31A

    Status: VALIDATED

    Source sequence(s)
    CR847788
    UniProtKB/TrEMBL
    A0A8M1PE08, F1R5G5
    Related
    ENSDARP00000104171.2, ENSDART00000108587.4
    Conserved Domains (4) summary
    COG2319
    Location:88407
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:1369
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:86337
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl14807
    Location:573770
    ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    5092500..5135788 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021479100.1XP_021334775.1  protein transport protein Sec31A isoform X7

    UniProtKB/TrEMBL
    A0A8M9QKI6
    Conserved Domains (4) summary
    sd00039
    Location:1369
    7WD40; WD40 repeat [structural motif]
    cl14807
    Location:8811078
    ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
    cl25539
    Location:86337
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl27975
    Location:11521297
    EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)
  2. XM_009305092.3XP_009303367.1  protein transport protein Sec31A isoform X5

    UniProtKB/TrEMBL
    A0A8M3AWH9
    Conserved Domains (4) summary
    COG2319
    Location:88407
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:1369
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:86337
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl14807
    Location:8811078
    ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
  3. XM_009305094.3XP_009303369.1  protein transport protein Sec31A isoform X6

    UniProtKB/TrEMBL
    A0A8M3BCT3
    Conserved Domains (4) summary
    COG2319
    Location:88407
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:1369
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:86337
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl14807
    Location:8811078
    ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
  4. XM_009305091.3XP_009303366.1  protein transport protein Sec31A isoform X4

    UniProtKB/TrEMBL
    A0A8M3B316
    Conserved Domains (4) summary
    COG2319
    Location:88407
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:1369
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:86337
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl14807
    Location:8811078
    ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
  5. XM_009305090.3XP_009303365.1  protein transport protein Sec31A isoform X3

    UniProtKB/TrEMBL
    A0A8M3B600
    Conserved Domains (4) summary
    COG2319
    Location:88407
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:1369
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:86337
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl14807
    Location:8811078
    ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
  6. XM_009305089.3XP_009303364.1  protein transport protein Sec31A isoform X2

    UniProtKB/TrEMBL
    A0A8M3AWG1
    Conserved Domains (4) summary
    COG2319
    Location:88407
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:1369
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:86337
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl14807
    Location:8811078
    ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
  7. XM_009305088.3XP_009303363.1  protein transport protein Sec31A isoform X1

    UniProtKB/TrEMBL
    A0A8M3BCS9
    Conserved Domains (4) summary
    COG2319
    Location:88407
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:1369
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:86337
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl14807
    Location:8811078
    ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394763.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    149908..194564 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395286.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    142834..211381 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)