Format

Send to:

Choose Destination

id2a inhibitor of DNA binding 2a [ Danio rerio (zebrafish) ]

Gene ID: 266599, updated on 3-Oct-2019

Summary

Official Symbol
id2aprovided by ZNC
Official Full Name
inhibitor of DNA binding 2aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-020910-1
See related
Ensembl:ENSDARG00000055283
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
id2; cb321; wu:fa04e03

Genomic context

See id2a in Genome Data Viewer
Location:
chromosome: 17
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (34805939..34808165)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (34857993..34860219)
103 previous assembly Zv9 (GCF_000002035.4) 17 NC_007128.5 (34973069..34975295)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110438045 Neighboring gene uncharacterized LOC103909053 Neighboring gene putative uncharacterized protein DDB_G0286901 Neighboring gene kinase D-interacting substrate 220a Neighboring gene membrane bound O-acyltransferase domain containing 2a

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

  • Canonical wnt signaling, organism-specific biosystem (from WikiPathways)
    Canonical wnt signaling, organism-specific biosystem
    Canonical wnt signaling
  • Id Signaling Pathway, organism-specific biosystem (from WikiPathways)
    Id Signaling Pathway, organism-specific biosystemInhibitor of DNA binding (ID) proteins are members of the helix-loop-helix (HLH) family of proteins which lack a DNA binding domain themselves but bind to other family members inhibiting their DNA bi...
  • Neural crest development, organism-specific biosystem (from WikiPathways)
    Neural crest development, organism-specific biosystemThis pathway displays genes required for different processes in neural crest development. It is based on genetic and signaling interactions.
  • TGF-beta signaling pathway, organism-specific biosystem (from KEGG)
    TGF-beta signaling pathway, organism-specific biosystemThe transforming growth factor-beta (TGF-beta) family members, which include TGF-betas, activins and bone morphogenetic proteins (BMPs), are structurally related secreted cytokines found in species r...
  • TGF-beta signaling pathway, conserved biosystem (from KEGG)
    TGF-beta signaling pathway, conserved biosystemThe transforming growth factor-beta (TGF-beta) family members, which include TGF-betas, activins and bone morphogenetic proteins (BMPs), are structurally related secreted cytokines found in species r...

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
circadian rhythm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
intra-S DNA damage checkpoint IMP
Inferred from Mutant Phenotype
more info
PubMed 
liver development IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of Notch signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of Notch signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of cell proliferation involved in compound eye morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of photoreceptor cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of retina development in camera-type eye IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
colocalizes_with cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
DNA-binding protein inhibitor ID-2
Names
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201291.1NP_958448.1  DNA-binding protein inhibitor ID-2

    See identical proteins and their annotated locations for NP_958448.1

    Status: PROVISIONAL

    Source sequence(s)
    BC056303
    UniProtKB/TrEMBL
    Q7SZQ2
    Related
    ENSDARP00000072092.3, ENSDART00000077626.4
    Conserved Domains (1) summary
    cd00083
    Location:4283
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    34805939..34808165
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center