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OR7E24 olfactory receptor family 7 subfamily E member 24 [ Homo sapiens (human) ]

Gene ID: 26648, updated on 26-Oct-2022

Summary

Official Symbol
OR7E24provided by HGNC
Official Full Name
olfactory receptor family 7 subfamily E member 24provided by HGNC
Primary source
HGNC:HGNC:8396
See related
Ensembl:ENSG00000237521 AllianceGenome:HGNC:8396
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HSHT2; OR19-8; OR7E24P; OR7E24Q
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR7E24 in Genome Data Viewer
Location:
19p13.2
Exon count:
6
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (9206488..9252625)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (9373546..9378827)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (9358020..9363301)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 7 subfamily E member 16 pseudogene Neighboring gene olfactory receptor family 7 subfamily E member 25 pseudogene Neighboring gene olfactory receptor family 7 subfamily D member 4 Neighboring gene olfactory receptor family 7 subfamily D member 11 pseudogene Neighboring gene olfactory receptor family 7 subfamily D member 1 pseudogene Neighboring gene olfactory receptor family 7 subfamily E member 18 pseudogene Neighboring gene olfactory receptor family 7 subfamily E member 19 pseudogene

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
olfactory receptor 7E24
Names
olfactory receptor OR19-14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079935.2NP_001073404.1  olfactory receptor 7E24 isoform 1

    See identical proteins and their annotated locations for NP_001073404.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AC006271
    Consensus CDS
    CCDS45955.1
    UniProtKB/Swiss-Prot
    Q6IFN5, Q9UPJ1
    Related
    ENSP00000387523.1, ENST00000456448.3
    Conserved Domains (2) summary
    pfam00001
    Location:59308
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:49322
    7tm_4; Olfactory receptor
  2. NM_001386108.1NP_001373037.1  olfactory receptor 7E24 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC006271
    Consensus CDS
    CCDS92506.1
    UniProtKB/TrEMBL
    A0A2R8Y4Q1
    Related
    ENSP00000494223.1, ENST00000641946.1
    Conserved Domains (1) summary
    cd15234
    Location:39315
    7tmA_OR7-like; olfactory receptor family 7 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    9206488..9252625
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047438597.1XP_047294553.1  olfactory receptor 7E24 isoform X3

  2. XM_047438594.1XP_047294550.1  olfactory receptor 7E24 isoform X1

  3. XM_047438596.1XP_047294552.1  olfactory receptor 7E24 isoform X3

  4. XM_047438598.1XP_047294554.1  olfactory receptor 7E24 isoform X3

  5. XM_047438595.1XP_047294551.1  olfactory receptor 7E24 isoform X2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    9373546..9378827
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)