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Slc27a3 solute carrier family 27 (fatty acid transporter), member 3 [ Mus musculus (house mouse) ]

Gene ID: 26568, updated on 24-Jan-2023

Summary

Official Symbol
Slc27a3provided by MGI
Official Full Name
solute carrier family 27 (fatty acid transporter), member 3provided by MGI
Primary source
MGI:MGI:1347358
See related
Ensembl:ENSMUSG00000027932 AllianceGenome:MGI:1347358
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
FATP3; Acsvl3; FATP-3; Vlcs-3
Summary
Enables fatty-acyl-CoA synthase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to act upstream of or within acyl-CoA metabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skeleton. Orthologous to human SLC27A3 (solute carrier family 27 member 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in adrenal adult (RPKM 148.3), ovary adult (RPKM 32.5) and 7 other tissues See more
Orthologs
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Genomic context

See Slc27a3 in Genome Data Viewer
Location:
3; 3 F1
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (90292540..90298693, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (90385230..90390835, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene DENN domain containing 4B Neighboring gene microRNA 7012 Neighboring gene GATA zinc finger domain containing 2B Neighboring gene integrator complex subunit 3 Neighboring gene natriuretic peptide receptor 1 Neighboring gene nuclear encoded tRNA methionine 11 (anticodon CAT)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables arachidonate-CoA ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables fatty-acyl-CoA synthase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables long-chain fatty acid transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables long-chain fatty acid-CoA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables long-chain fatty acid-CoA ligase activity ISO
Inferred from Sequence Orthology
more info
 
enables long-chain fatty acid-CoA ligase activity TAS
Traceable Author Statement
more info
PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables very long-chain fatty acid-CoA ligase activity ISO
Inferred from Sequence Orthology
more info
 
enables very long-chain fatty acid-CoA ligase activity TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial matrix TAS
Traceable Author Statement
more info
 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
long-chain fatty acid transport protein 3; solute carrier family 27 member 3
Names
arachidonate--CoA ligase
long-chain-fatty-acid--CoA ligase
mFLJ00207 protein
very long-chain acyl-CoA synthetase homolog 3
NP_001303617.1
NP_036118.2
XP_011238431.1
XP_011238432.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001316688.2NP_001303617.1  long-chain fatty acid transport protein 3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC145082
    UniProtKB/Swiss-Prot
    O88561
    Related
    ENSMUSP00000122599.2, ENSMUST00000132041.2
    Conserved Domains (1) summary
    cl17068
    Location:64528
    AFD_class_I; Adenylate forming domain, Class I superfamily
  2. NM_011988.4NP_036118.2  long-chain fatty acid transport protein 3 isoform 1 precursor

    See identical proteins and their annotated locations for NP_036118.2

    Status: VALIDATED

    Source sequence(s)
    AC145082
    Consensus CDS
    CCDS17527.1
    UniProtKB/Swiss-Prot
    O88561
    UniProtKB/TrEMBL
    G3X8Y7
    Related
    ENSMUSP00000029541.6, ENSMUST00000029541.12
    Conserved Domains (2) summary
    PRK08279
    Location:62666
    PRK08279; long-chain-acyl-CoA synthetase; Validated
    cl17068
    Location:88657
    AFD_class_I; Adenylate forming domain, Class I superfamily

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    90292540..90298693 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011240129.4XP_011238431.1  solute carrier family 27 member 3 isoform X1

    Conserved Domains (1) summary
    cl17068
    Location:87609
    AFD_class_I; Adenylate forming domain, Class I superfamily
  2. XM_011240130.3XP_011238432.1  solute carrier family 27 member 3 isoform X2

    Conserved Domains (1) summary
    cl17068
    Location:37480
    AFD_class_I; Adenylate forming domain, Class I superfamily