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Ncdn neurochondrin [ Mus musculus (house mouse) ]

Gene ID: 26562, updated on 21-May-2024

Summary

Official Symbol
Ncdnprovided by MGI
Official Full Name
neurochondrinprovided by MGI
Primary source
MGI:MGI:1347351
See related
Ensembl:ENSMUSG00000028833 AllianceGenome:MGI:1347351
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ms10ae; norbin; MMS10-AE; mKIAA0607
Summary
Involved in neuron projection development. Acts upstream of or within bone resorption. Located in neuron projection. Is expressed in several structures, including central nervous system; dorsal root ganglion; femur; and tendon. Orthologous to human NCDN (neurochondrin). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in frontal lobe adult (RPKM 191.8), cortex adult (RPKM 179.9) and 17 other tissues See more
Orthologs
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Genomic context

See Ncdn in Genome Data Viewer
Location:
4; 4 D2.2
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (126637548..126647203, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (126743750..126753765, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr4:126354636-126354937 Neighboring gene proteasome (prosome, macropain) subunit, beta type 2 Neighboring gene transcription factor AP-2, epsilon Neighboring gene STARR-positive B cell enhancer mm9_chr4:126430552-126430853 Neighboring gene expressed sequence AU040320 Neighboring gene predicted gene, 24161 Neighboring gene predicted gene, 25604

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in dendrite IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in dendrite ISO
Inferred from Sequence Orthology
more info
 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in endosome membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in neuron projection IDA
Inferred from Direct Assay
more info
PubMed 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
located_in perikaryon ISO
Inferred from Sequence Orthology
more info
 
is_active_in postsynapse IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in postsynapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in postsynapse ISO
Inferred from Sequence Orthology
more info
 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
neurochondrin
Names
M-Sema F-associating protein of 75 kDa
minisatellite 10ae detected by probe MMS10
neurochondrin-1
neurochondrin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355412.2NP_001342341.1  neurochondrin isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL606908
    Conserved Domains (1) summary
    pfam05536
    Location:13620
    Neurochondrin
  2. NM_001355413.2NP_001342342.1  neurochondrin isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL606908
    Conserved Domains (1) summary
    pfam05536
    Location:13620
    Neurochondrin
  3. NM_001424941.1NP_001411870.1  neurochondrin isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL606908
    UniProtKB/Swiss-Prot
    Q3TCW4, Q80TW1, Q91YH7, Q9CW81, Q9QUQ0, Q9Z0E0
    Related
    ENSMUSP00000101722.2, ENSMUST00000106116.2
  4. NM_001424942.1NP_001411871.1  neurochondrin isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL606908
  5. NM_001424943.1NP_001411872.1  neurochondrin isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL606908
  6. NM_001424944.1NP_001411873.1  neurochondrin isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL606908
  7. NM_001424945.1NP_001411874.1  neurochondrin isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL606908
  8. NM_011986.5NP_036116.3  neurochondrin isoform 1

    See identical proteins and their annotated locations for NP_036116.3

    Status: VALIDATED

    Source sequence(s)
    AL606908
    Consensus CDS
    CCDS18659.1
    UniProtKB/Swiss-Prot
    Q3TCW4, Q80TW1, Q91YH7, Q9CW81, Q9QUQ0, Q9Z0E0
    Related
    ENSMUSP00000030637.8, ENSMUST00000030637.14
    Conserved Domains (1) summary
    pfam05536
    Location:30637
    Neurochondrin

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    126637548..126647203 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)