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OR10J1 olfactory receptor family 10 subfamily J member 1 [ Homo sapiens (human) ]

Gene ID: 26476, updated on 25-Nov-2021

Summary

Official Symbol
OR10J1provided by HGNC
Official Full Name
olfactory receptor family 10 subfamily J member 1provided by HGNC
Primary source
HGNC:HGNC:8175
See related
Ensembl:ENSG00000196184
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HGMP07J; HSHGMP07J
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Restricted expression toward testis (RPKM 1.9) See more
Orthologs
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Genomic context

See OR10J1 in Genome Data Viewer
Location:
1q23.2
Exon count:
5
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (159397465..159440967)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (159367255..159410757)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 10 subfamily J member 7 pseudogene Neighboring gene olfactory receptor family 10 subfamily J member 8 pseudogene Neighboring gene olfactory receptor family 10 subfamily J member 9 pseudogene Neighboring gene Sharpr-MPRA regulatory region 7346 Neighboring gene olfactory receptor family 10 subfamily J member 4 (gene/pseudogene) Neighboring gene long intergenic non-protein coding RNA 2819 Neighboring gene olfactory receptor family 10 subfamily J member 5

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
Chemerin, a novel adipokine in the regulation of angiogenesis.
GeneReviews: Not available
Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.
GeneReviews: Not available
Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women.
GeneReviews: Not available
Genome-wide association with select biomarker traits in the Framingham Heart Study.
GeneReviews: Not available
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
GeneReviews: Not available

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC138495, MGC138497

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables odorant binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of plasma membrane TAS
Traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
olfactory receptor 10J1
Names
olfactory receptor OR1-26
olfactory receptor-like protein HGMP07J

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001363557.2NP_001350486.1  olfactory receptor 10J1

    Status: VALIDATED

    Source sequence(s)
    AL513323, AL663023
    Conserved Domains (1) summary
    cd15225
    Location:25300
    7tmA_OR10A-like; olfactory receptor subfamily 10A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. NM_001363558.2NP_001350487.1  olfactory receptor 10J1

    Status: VALIDATED

    Source sequence(s)
    AL513323, AL663023
    Consensus CDS
    CCDS86023.1
    Conserved Domains (1) summary
    cd15225
    Location:25300
    7tmA_OR10A-like; olfactory receptor subfamily 10A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
  3. NM_012351.3NP_036483.3  olfactory receptor 10J1

    Status: VALIDATED

    Source sequence(s)
    AL663023, BC069150
    Consensus CDS
    CCDS1185.1
    Related
    ENSP00000399078.4, ENST00000423932.6
    Conserved Domains (1) summary
    cd15225
    Location:25300
    7tmA_OR10A-like; olfactory receptor subfamily 10A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    159397465..159440967
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006711271.3XP_006711334.1  olfactory receptor 10J1 isoform X1

    See identical proteins and their annotated locations for XP_006711334.1

    UniProtKB/TrEMBL
    A0A126GWQ9
    Conserved Domains (1) summary
    cd15225
    Location:25300
    7tmA_OR10A-like; olfactory receptor subfamily 10A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. XM_017001015.1XP_016856504.1  olfactory receptor 10J1 isoform X1

    UniProtKB/TrEMBL
    A0A126GWQ9
    Related
    ENSP00000493228.1, ENST00000642080.1
    Conserved Domains (1) summary
    cd15225
    Location:25300
    7tmA_OR10A-like; olfactory receptor subfamily 10A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
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