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Git2 GIT ArfGAP 2 [ Mus musculus (house mouse) ]

Gene ID: 26431, updated on 12-May-2024

Summary

Official Symbol
Git2provided by MGI
Official Full Name
GIT ArfGAP 2provided by MGI
Primary source
MGI:MGI:1347053
See related
Ensembl:ENSMUSG00000041890 AllianceGenome:MGI:1347053
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CAT2; mKIAA0148; 1500036H07Rik; 5830420E16Rik; 6430510B20Rik; 9630056M03Rik; B230104M05Rik
Summary
Predicted to enable GTPase activator activity and metal ion binding activity. Involved in presynaptic modulation of chemical synaptic transmission and regulation of synaptic vesicle exocytosis. Acts upstream of or within behavioral response to pain. Is active in calyx of Held. Is expressed in genitourinary system. Orthologous to human GIT2 (GIT ArfGAP 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 38.4), lung adult (RPKM 24.5) and 28 other tissues See more
Orthologs
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Genomic context

See Git2 in Genome Data Viewer
Location:
5 F; 5 55.99 cM
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (114865469..114912647, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (114727408..114774588, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 34931 Neighboring gene STARR-positive B cell enhancer ABC_E10341 Neighboring gene trichoplein, keratin filament binding Neighboring gene microRNA 7028 Neighboring gene RIKEN cDNA 4930515G01 gene Neighboring gene STARR-positive B cell enhancer ABC_E3602 Neighboring gene ankyrin repeat domain 13a Neighboring gene STARR-positive B cell enhancer ABC_E3603 Neighboring gene STARR-seq mESC enhancer starr_14089 Neighboring gene RIKEN cDNA 1500011B03 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • KIAA0148

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein-containing complex binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables small GTPase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in calyx of Held IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in calyx of Held IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in presynapse IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in synapse IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
ARF GTPase-activating protein GIT2
Names
ARF GAP GIT2
ARF GTPase activating protein 2
G protein-coupled receptor kinase-interactor 2
GRK-interacting protein 2
cool-interacting tyrosine-phosphorylated protein 2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077359.2NP_001070827.1  ARF GTPase-activating protein GIT2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC087330
    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (6) summary
    smart00105
    Location:2124
    ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
    cd00204
    Location:109220
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam08518
    Location:267295
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:559673
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137229
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:137165
    ANK; ANK repeat [structural motif]
  2. NM_001077360.2NP_001070828.1  ARF GTPase-activating protein GIT2 isoform 3

    See identical proteins and their annotated locations for NP_001070828.1

    Status: VALIDATED

    Source sequence(s)
    AC087330
    Consensus CDS
    CCDS39223.1
    UniProtKB/TrEMBL
    J3QK07, Q6PGJ1, Q80XR8
    Related
    ENSMUSP00000039718.8, ENSMUST00000043283.14
    Conserved Domains (6) summary
    smart00105
    Location:2124
    ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
    cd00204
    Location:109220
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam08518
    Location:266294
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:558672
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137229
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:137165
    ANK; ANK repeat [structural motif]
  3. NM_001347400.2NP_001334329.1  ARF GTPase-activating protein GIT2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC087330
    Consensus CDS
    CCDS84939.1
    UniProtKB/TrEMBL
    E9PVA6, J3QK07
    Related
    ENSMUSP00000083754.5, ENSMUST00000086564.11
  4. NM_001429058.1NP_001415987.1  ARF GTPase-activating protein GIT2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC087330
  5. NM_001429059.1NP_001415988.1  ARF GTPase-activating protein GIT2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC087330
  6. NM_001429060.1NP_001415989.1  ARF GTPase-activating protein GIT2 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC087330
  7. NM_001429061.1NP_001415990.1  ARF GTPase-activating protein GIT2 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC087330
  8. NM_001429062.1NP_001415991.1  ARF GTPase-activating protein GIT2 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC087330
  9. NM_001429063.1NP_001415992.1  ARF GTPase-activating protein GIT2 isoform 10

    Status: VALIDATED

    Source sequence(s)
    AC087330
  10. NM_001429064.1NP_001415993.1  ARF GTPase-activating protein GIT2 isoform 11

    Status: VALIDATED

    Source sequence(s)
    AC087330
  11. NM_001429065.1NP_001415994.1  ARF GTPase-activating protein GIT2 isoform 12

    Status: VALIDATED

    Source sequence(s)
    AC087330
  12. NM_001429066.1NP_001415995.1  ARF GTPase-activating protein GIT2 isoform 13

    Status: VALIDATED

    Source sequence(s)
    AC087330
  13. NM_001429067.1NP_001415996.1  ARF GTPase-activating protein GIT2 isoform 14

    Status: VALIDATED

    Source sequence(s)
    AC087330
  14. NM_001429068.1NP_001415997.1  ARF GTPase-activating protein GIT2 isoform 15

    Status: VALIDATED

    Source sequence(s)
    AC087330
  15. NM_001429069.1NP_001415998.1  ARF GTPase-activating protein GIT2 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC087330
  16. NM_001429070.1NP_001415999.1  ARF GTPase-activating protein GIT2 isoform 17

    Status: VALIDATED

    Source sequence(s)
    AC087330
  17. NM_001429071.1NP_001416000.1  ARF GTPase-activating protein GIT2 isoform 18

    Status: VALIDATED

    Source sequence(s)
    AC087330
  18. NM_001429072.1NP_001416001.1  ARF GTPase-activating protein GIT2 isoform 19

    Status: VALIDATED

    Source sequence(s)
    AC087330
  19. NM_001429073.1NP_001416002.1  ARF GTPase-activating protein GIT2 isoform 20

    Status: VALIDATED

    Source sequence(s)
    AC087330
  20. NM_001429074.1NP_001416003.1  ARF GTPase-activating protein GIT2 isoform 21

    Status: VALIDATED

    Source sequence(s)
    AC087330
  21. NM_001429075.1NP_001416004.1  ARF GTPase-activating protein GIT2 isoform 22

    Status: VALIDATED

    Source sequence(s)
    AC087330
  22. NM_001429076.1NP_001416005.1  ARF GTPase-activating protein GIT2 isoform 23

    Status: VALIDATED

    Source sequence(s)
    AC087330
  23. NM_001429077.1NP_001416006.1  ARF GTPase-activating protein GIT2 isoform 24

    Status: VALIDATED

    Source sequence(s)
    AC087330
  24. NM_001429078.1NP_001416007.1  ARF GTPase-activating protein GIT2 isoform 25

    Status: VALIDATED

    Source sequence(s)
    AC087330
  25. NM_001429079.1NP_001416008.1  ARF GTPase-activating protein GIT2 isoform 26

    Status: VALIDATED

    Source sequence(s)
    AC087330
  26. NM_001429080.1NP_001416009.1  ARF GTPase-activating protein GIT2 isoform 27

    Status: VALIDATED

    Source sequence(s)
    AC087330
  27. NM_001429081.1NP_001416010.1  ARF GTPase-activating protein GIT2 isoform 28

    Status: VALIDATED

    Source sequence(s)
    AC087330
  28. NM_001429082.1NP_001416011.1  ARF GTPase-activating protein GIT2 isoform 29

    Status: VALIDATED

    Source sequence(s)
    AC087330
  29. NM_001429083.1NP_001416012.1  ARF GTPase-activating protein GIT2 isoform 30

    Status: VALIDATED

    Source sequence(s)
    AC087330
  30. NM_001429084.1NP_001416013.1  ARF GTPase-activating protein GIT2 isoform 31

    Status: VALIDATED

    Source sequence(s)
    AC087330
  31. NM_001429085.1NP_001416014.1  ARF GTPase-activating protein GIT2 isoform 32

    Status: VALIDATED

    Source sequence(s)
    AC087330
  32. NM_001429086.1NP_001416015.1  ARF GTPase-activating protein GIT2 isoform 33

    Status: VALIDATED

    Source sequence(s)
    AC087330
  33. NM_001429087.1NP_001416016.1  ARF GTPase-activating protein GIT2 isoform 34

    Status: VALIDATED

    Source sequence(s)
    AC087330
  34. NM_019834.4NP_062808.3  ARF GTPase-activating protein GIT2 isoform 1

    See identical proteins and their annotated locations for NP_062808.3

    Status: VALIDATED

    Source sequence(s)
    AC087330
    Consensus CDS
    CCDS19570.2
    UniProtKB/Swiss-Prot
    E9QPU7, Q9JLQ2
    UniProtKB/TrEMBL
    J3QK07
    Related
    ENSMUSP00000107803.3, ENSMUST00000112185.9
    Conserved Domains (6) summary
    smart00105
    Location:2124
    ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
    cd00204
    Location:109220
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam08518
    Location:265293
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:587701
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137229
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:137165
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    114865469..114912647 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006530331.4XP_006530394.1  ARF GTPase-activating protein GIT2 isoform X2

    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (6) summary
    sd00045
    Location:137165
    ANK; ANK repeat [structural motif]
    cd08847
    Location:1111
    ArfGap_GIT2; GIT2 GTPase activating protein for Arf
    pfam08518
    Location:267295
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:639753
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137229
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:415479
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
  2. XM_006530334.4XP_006530397.1  ARF GTPase-activating protein GIT2 isoform X4

    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (6) summary
    sd00045
    Location:137165
    ANK; ANK repeat [structural motif]
    cd08847
    Location:1111
    ArfGap_GIT2; GIT2 GTPase activating protein for Arf
    pfam08518
    Location:268296
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:625739
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137229
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:416465
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
  3. XM_006530335.4XP_006530398.1  ARF GTPase-activating protein GIT2 isoform X7

    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (6) summary
    sd00045
    Location:137165
    ANK; ANK repeat [structural motif]
    cd08847
    Location:1111
    ArfGap_GIT2; GIT2 GTPase activating protein for Arf
    pfam08518
    Location:268296
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:610724
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137229
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:416480
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
  4. XM_006530339.4XP_006530402.1  ARF GTPase-activating protein GIT2 isoform X1

    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (6) summary
    sd00045
    Location:137165
    ANK; ANK repeat [structural motif]
    cd08847
    Location:1111
    ArfGap_GIT2; GIT2 GTPase activating protein for Arf
    pfam08518
    Location:268296
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:640754
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137229
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:416480
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
  5. XM_030254527.1XP_030110387.1  ARF GTPase-activating protein GIT2 isoform X17

    UniProtKB/TrEMBL
    J3QK07
    Related
    ENSMUSP00000136796.2, ENSMUST00000178440.8
    Conserved Domains (5) summary
    sd00045
    Location:137165
    ANK; ANK repeat [structural motif]
    cd08847
    Location:1111
    ArfGap_GIT2; GIT2 GTPase activating protein for Arf
    pfam08518
    Location:265293
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:557671
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137229
    Ank_2; Ankyrin repeats (3 copies)
  6. XM_030254522.2XP_030110382.1  ARF GTPase-activating protein GIT2 isoform X6

    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (6) summary
    sd00045
    Location:137165
    ANK; ANK repeat [structural motif]
    cd08847
    Location:1111
    ArfGap_GIT2; GIT2 GTPase activating protein for Arf
    pfam08518
    Location:265293
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:622736
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137229
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:413462
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
  7. XM_006530333.5XP_006530396.1  ARF GTPase-activating protein GIT2 isoform X3

    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (6) summary
    sd00045
    Location:137165
    ANK; ANK repeat [structural motif]
    cd08847
    Location:1111
    ArfGap_GIT2; GIT2 GTPase activating protein for Arf
    pfam08518
    Location:265293
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:637751
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137229
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:413477
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
  8. XM_017320893.3XP_017176382.1  ARF GTPase-activating protein GIT2 isoform X12

    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (5) summary
    sd00045
    Location:137165
    ANK; ANK repeat [structural motif]
    cd08847
    Location:1111
    ArfGap_GIT2; GIT2 GTPase activating protein for Arf
    pfam08518
    Location:266294
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:588702
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137229
    Ank_2; Ankyrin repeats (3 copies)
  9. XM_030254520.2XP_030110380.1  ARF GTPase-activating protein GIT2 isoform X5

    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (6) summary
    sd00045
    Location:137165
    ANK; ANK repeat [structural motif]
    cd08847
    Location:1111
    ArfGap_GIT2; GIT2 GTPase activating protein for Arf
    pfam08518
    Location:266294
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:623737
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137229
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:414463
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
  10. XM_006530336.5XP_006530399.1  ARF GTPase-activating protein GIT2 isoform X8

    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (6) summary
    sd00045
    Location:137165
    ANK; ANK repeat [structural motif]
    cd08847
    Location:1111
    ArfGap_GIT2; GIT2 GTPase activating protein for Arf
    pfam08518
    Location:266294
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:608722
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137229
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:414478
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
  11. XM_006530338.5XP_006530401.1  ARF GTPase-activating protein GIT2 isoform X16

    UniProtKB/TrEMBL
    D3Z1I2, J3QK07
    Related
    ENSMUSP00000107801.2, ENSMUST00000112183.8
    Conserved Domains (5) summary
    sd00045
    Location:137165
    ANK; ANK repeat [structural motif]
    cd08847
    Location:1111
    ArfGap_GIT2; GIT2 GTPase activating protein for Arf
    pfam08518
    Location:268296
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:560674
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137229
    Ank_2; Ankyrin repeats (3 copies)
  12. XM_006530337.5XP_006530400.1  ARF GTPase-activating protein GIT2 isoform X11

    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (5) summary
    sd00045
    Location:137165
    ANK; ANK repeat [structural motif]
    cd08847
    Location:1111
    ArfGap_GIT2; GIT2 GTPase activating protein for Arf
    pfam08518
    Location:268296
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:590704
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137229
    Ank_2; Ankyrin repeats (3 copies)
  13. XM_030254524.2XP_030110384.1  ARF GTPase-activating protein GIT2 isoform X10

    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (6) summary
    sd00045
    Location:137165
    ANK; ANK repeat [structural motif]
    cd08847
    Location:1111
    ArfGap_GIT2; GIT2 GTPase activating protein for Arf
    pfam08518
    Location:268296
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:595709
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137229
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:416465
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
  14. XM_030254526.2XP_030110386.1  ARF GTPase-activating protein GIT2 isoform X15

    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (6) summary
    sd00045
    Location:75103
    ANK; ANK repeat [structural motif]
    cl28907
    Location:149
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
    pfam08518
    Location:203231
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:575689
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:75167
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:351415
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
  15. XM_036165144.1XP_036021037.1  ARF GTPase-activating protein GIT2 isoform X14

    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (6) summary
    sd00045
    Location:75103
    ANK; ANK repeat [structural motif]
    cl28907
    Location:149
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
    pfam08518
    Location:204232
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:574690
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:75167
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:352416
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
  16. XM_030254525.2XP_030110385.1  ARF GTPase-activating protein GIT2 isoform X13

    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (6) summary
    sd00045
    Location:75103
    ANK; ANK repeat [structural motif]
    cl28907
    Location:149
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
    pfam08518
    Location:206234
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:578692
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:75167
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:354418
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
  17. XM_030254529.2XP_030110389.1  ARF GTPase-activating protein GIT2 isoform X19

    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (5) summary
    sd00045
    Location:75103
    ANK; ANK repeat [structural motif]
    cl28907
    Location:149
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
    pfam08518
    Location:203231
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:525639
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:75167
    Ank_2; Ankyrin repeats (3 copies)
  18. XM_030254530.2XP_030110390.1  ARF GTPase-activating protein GIT2 isoform X20

    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (5) summary
    sd00045
    Location:75103
    ANK; ANK repeat [structural motif]
    cl28907
    Location:149
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
    pfam08518
    Location:204232
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:496610
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:75167
    Ank_2; Ankyrin repeats (3 copies)
  19. XM_030254528.2XP_030110388.1  ARF GTPase-activating protein GIT2 isoform X18

    UniProtKB/TrEMBL
    J3QK07
    Conserved Domains (5) summary
    sd00045
    Location:75103
    ANK; ANK repeat [structural motif]
    cl28907
    Location:149
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
    pfam08518
    Location:204232
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:526640
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:75167
    Ank_2; Ankyrin repeats (3 copies)
  20. XM_030254523.2XP_030110383.1  ARF GTPase-activating protein GIT2 isoform X9

    UniProtKB/TrEMBL
    J3QK07
    Related
    ENSMUSP00000122302.3, ENSMUST00000155908.8
    Conserved Domains (6) summary
    sd00045
    Location:137165
    ANK; ANK repeat [structural motif]
    cd08847
    Location:1111
    ArfGap_GIT2; GIT2 GTPase activating protein for Arf
    pfam08518
    Location:265293
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:607721
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:137229
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:413477
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor