Format

Send to:

Choose Destination

FAM162A family with sequence similarity 162 member A [ Homo sapiens (human) ]

Gene ID: 26355, updated on 7-Oct-2018

Summary

Official Symbol
FAM162Aprovided by HGNC
Official Full Name
family with sequence similarity 162 member Aprovided by HGNC
Primary source
HGNC:HGNC:17865
See related
Ensembl:ENSG00000114023 MIM:608017; Vega:OTTHUMG00000159494
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
E2IG5; HGTD-P; C3orf28
Expression
Ubiquitous expression in colon (RPKM 86.7), esophagus (RPKM 60.9) and 25 other tissues See more
Orthologs

Genomic context

See FAM162A in Genome Data Viewer
Location:
3q21.1
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 3 NC_000003.12 (122384176..122410114)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (122103023..122128961)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene cystatin A Neighboring gene HNF4 motif-containing MPRA enhancer 1/2 Neighboring gene coiled-coil domain containing 58 Neighboring gene uncharacterized LOC102723582 Neighboring gene WD repeat domain 5B Neighboring gene karyopherin subunit alpha 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
protein FAM162A
Names
E2-induced gene 5 protein
HIF-1 alpha-responsive proapoptotic molecule
growth and transformation-dependent protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014367.3NP_055182.3  protein FAM162A

    See identical proteins and their annotated locations for NP_055182.3

    Status: VALIDATED

    Source sequence(s)
    AF201944, AF250321, BI460077
    Consensus CDS
    CCDS43139.1
    UniProtKB/Swiss-Prot
    Q96A26
    UniProtKB/TrEMBL
    Q9H2P1
    Related
    ENSP00000419088.1, OTTHUMP00000215578, ENST00000477892.5, OTTHUMT00000355766
    Conserved Domains (1) summary
    pfam06388
    Location:33152
    DUF1075; Protein of unknown function (DUF1075)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p12 Primary Assembly

    Range
    122384176..122410114
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center