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RSL1D1 ribosomal L1 domain containing 1 [ Homo sapiens (human) ]

Gene ID: 26156, updated on 7-Aug-2022

Summary

Official Symbol
RSL1D1provided by HGNC
Official Full Name
ribosomal L1 domain containing 1provided by HGNC
Primary source
HGNC:HGNC:24534
See related
Ensembl:ENSG00000171490 MIM:615874; AllianceGenome:HGNC:24534
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
L12; CSIG; PBK1; UTP30
Summary
Enables mRNA 3'-UTR binding activity and mRNA 5'-UTR binding activity. Involved in regulation of apoptotic process and regulation of cellular senescence. Acts upstream of or within regulation of protein localization. Located in chromosome and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary (RPKM 45.7), lymph node (RPKM 20.2) and 25 other tissues See more
Orthologs
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Genomic context

See RSL1D1 in Genome Data Viewer
Location:
16p13.13
Exon count:
9
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (11833850..11851542, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (11869901..11887593, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (11927707..11945399, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene zinc finger CCCH-type containing 7A Neighboring gene breast cancer anti-estrogen resistance 4 Neighboring gene G1 to S phase transition 1 Neighboring gene cytochrome c oxidase subunit 6C pseudogene 1 Neighboring gene nuclear pore complex interacting protein family member B2 Neighboring gene TNF receptor superfamily member 17

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of ribosomal L1 domain containing 1 (RSL1D1) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC138433, MGC142259, DKFZP564M182

General protein information

Preferred Names
ribosomal L1 domain-containing protein 1
Names
CATX-11
cellular senescence-inhibited gene protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015659.3NP_056474.2  ribosomal L1 domain-containing protein 1

    See identical proteins and their annotated locations for NP_056474.2

    Status: VALIDATED

    Source sequence(s)
    AC010654, BC113699, BI856275
    Consensus CDS
    CCDS10551.1
    UniProtKB/Swiss-Prot
    O76021, Q9Y3Z9
    Related
    ENSP00000460871.1, ENST00000571133.6
    Conserved Domains (2) summary
    cd00403
    Location:36263
    Ribosomal_L1; Ribosomal protein L1. The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA. In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds ...
    cl25751
    Location:324462
    DUF4045; Domain of unknown function (DUF4045)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    11833850..11851542 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    11869901..11887593 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)