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PYDC1 pyrin domain containing 1 [ Homo sapiens (human) ]

Gene ID: 260434, updated on 8-Jul-2018
Official Symbol
PYDC1provided by HGNC
Official Full Name
pyrin domain containing 1provided by HGNC
Primary source
HGNC:HGNC:30261
See related
Ensembl:ENSG00000169900 MIM:615700; Vega:OTTHUMG00000132407
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ASC2; POP1; PYC1; cPOP1
Expression
Biased expression in skin (RPKM 1.7), brain (RPKM 0.2) and 1 other tissue See more
Orthologs
See PYDC1 in Genome Data Viewer
Location:
16p11.2
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 16 NC_000016.10 (31215962..31217093, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (31227283..31228398, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene FUS RNA binding protein Neighboring gene PYCARD antisense RNA 1 Neighboring gene PYD and CARD domain containing Neighboring gene tripartite motif containing 72 Neighboring gene integrin subunit alpha M Neighboring gene integrin subunit alpha X pseudogene Neighboring gene integrin subunit alpha X

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • NOD-like receptor signaling pathway, organism-specific biosystem (from KEGG)
    NOD-like receptor signaling pathway, organism-specific biosystemSpecific families of pattern recognition receptors are responsible for detecting various pathogens and generating innate immune responses. The intracellular NOD-like receptor (NLR) family contains mo...
  • NOD-like receptor signaling pathway, conserved biosystem (from KEGG)
    NOD-like receptor signaling pathway, conserved biosystemSpecific families of pattern recognition receptors are responsible for detecting various pathogens and generating innate immune responses. The intracellular NOD-like receptor (NLR) family contains mo...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Preferred Names
pyrin domain-containing protein 1
Names
PAAD-only protein 1
PYD (pyrin domain) containing 1
cellular POP1
pyrin-only protein 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152901.3NP_690865.1  pyrin domain-containing protein 1

    See identical proteins and their annotated locations for NP_690865.1

    Status: VALIDATED

    Source sequence(s)
    AF086332
    Consensus CDS
    CCDS10710.1
    UniProtKB/Swiss-Prot
    Q8WXC3
    Related
    ENSP00000304336.3, OTTHUMP00000163243, ENST00000302964.3, OTTHUMT00000255543
    Conserved Domains (1) summary
    cd08321
    Location:587
    Pyrin_ASC-like; Pyrin Death Domain found in ASC

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p12 Primary Assembly

    Range
    31215962..31217093 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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