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SIPA1L1 signal induced proliferation associated 1 like 1 [ Homo sapiens (human) ]

Gene ID: 26037, updated on 24-Nov-2020

Summary

Official Symbol
SIPA1L1provided by HGNC
Official Full Name
signal induced proliferation associated 1 like 1provided by HGNC
Primary source
HGNC:HGNC:20284
See related
Ensembl:ENSG00000197555 MIM:617504
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
E6TP1; SPAR1
Expression
Ubiquitous expression in brain (RPKM 7.9), spleen (RPKM 7.4) and 25 other tissues See more
Orthologs

Genomic context

See SIPA1L1 in Genome Data Viewer
Location:
14q24.2
Exon count:
37
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (71320418..71741209)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (71788108..72207761)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105370706 Neighboring gene uncharacterized LOC107984654 Neighboring gene uncharacterized LOC102724015 Neighboring gene PDZ domain containing 11 pseudogene Neighboring gene small nucleolar RNA, C/D box 56B Neighboring gene RNA, 7SL, cytoplasmic 683, pseudogene Neighboring gene uncharacterized LOC145474 Neighboring gene regulator of G protein signaling 6 Neighboring gene uncharacterized LOC105370559 Neighboring gene microRNA 7843

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Phenotypes

Associated conditions

Description Tests
ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.
GeneReviews: Not available
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
GeneReviews: Not available

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ37213, KIAA0440, DKFZp686G1344

Gene Ontology Provided by GOA

Function Evidence Code Pubs
GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 
ephrin receptor binding IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
actin cytoskeleton reorganization ISS
Inferred from Sequence or Structural Similarity
more info
 
activation of GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
activation of GTPase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
biological_process ND
No biological Data available
more info
 
ephrin receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of GTPase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of axonogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of dendritic spine morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of small GTPase mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 
regulation of synaptic plasticity ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
dendritic spine ISS
Inferred from Sequence or Structural Similarity
more info
 
postsynaptic density ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
signal-induced proliferation-associated 1-like protein 1
Names
SIPA1-like protein 1
high-risk human papilloma viruses E6 oncoproteins targeted protein 1
spine-associated RapGAP 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001284245.3NP_001271174.1  signal-induced proliferation-associated 1-like protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001271174.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate in-frame exon, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Variants 2 and 10 both encode the same isoform (2).
    Source sequence(s)
    AC004900, AC004968, AC004974, AC005476, AC005994, AF090989, DA330003
    Consensus CDS
    CCDS61490.1
    UniProtKB/Swiss-Prot
    O43166
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17161771
    ZapB; Cell division protein ZapB
    pfam11881
    Location:14831728
    SPAR_C; C-terminal domain of SPAR protein
  2. NM_001284246.2NP_001271175.1  signal-induced proliferation-associated 1-like protein 1 isoform 3

    See identical proteins and their annotated locations for NP_001271175.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, lacks an alternate in-frame exon, uses an alternate in-frame splice site, compared to variant 1. The encoded isoform (3) is shorter than isoform 1. Variants 3, 6, 7, and 8 encode the same isoform (3).
    Source sequence(s)
    AC004900, AC004974, AF090989, AK122930
    Consensus CDS
    CCDS61491.1
    UniProtKB/Swiss-Prot
    O43166
    Related
    ENSP00000351352.2, ENST00000358550.6
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17151770
    ZapB; Cell division protein ZapB
    pfam11881
    Location:14831727
    SPAR_C; C-terminal domain of SPAR protein
  3. NM_001284247.3NP_001271176.1  signal-induced proliferation-associated 1-like protein 1 isoform 4

    See identical proteins and their annotated locations for NP_001271176.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and uses an alternate in-frame splice site, compared to variant 1. The encoded isoform (4) is shorter than isoform 1.
    Source sequence(s)
    AB007900, AC004900, AC004968, AL707661, BM697295, CR936651, DA034212, DA184827, DA265109, DA330003, DT219010
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17361791
    ZapB; Cell division protein ZapB
    pfam11881
    Location:15041748
    SPAR_C; C-terminal domain of SPAR protein
  4. NM_001354285.2NP_001341214.1  signal-induced proliferation-associated 1-like protein 1 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Both variants 1 and 5 encode the same isoform (1).
    Source sequence(s)
    AC004900, AC004968, AC004974, AC005476, AF090990, DA330003
    Consensus CDS
    CCDS9807.1
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17371792
    ZapB; Cell division protein ZapB
    pfam11881
    Location:15041749
    SPAR_C; C-terminal domain of SPAR protein
  5. NM_001354286.2NP_001341215.1  signal-induced proliferation-associated 1-like protein 1 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, lacks an alternate in-frame exon, uses an alternate in-frame splice site, compared to variant 1. The encoded isoform (3) is shorter than isoform 1. Variants 3, 6, 7, and 8 encode the same isoform (3).
    Source sequence(s)
    AC004900, AC004968, AC004974, AC005476, AC005994, AF090989, AK122930, DA330003
    Consensus CDS
    CCDS61491.1
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17151770
    ZapB; Cell division protein ZapB
    pfam11881
    Location:14831727
    SPAR_C; C-terminal domain of SPAR protein
  6. NM_001354287.2NP_001341216.1  signal-induced proliferation-associated 1-like protein 1 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR, lacks an alternate in-frame exon, uses an alternate in-frame splice site, compared to variant 1. The encoded isoform (3) is shorter than isoform 1. Variants 3, 6, 7, and 8 encode the same isoform (3).
    Source sequence(s)
    AC004900, AC004968, AC004974, AC005476, AF090989, AK122930, DA330003
    Consensus CDS
    CCDS61491.1
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17151770
    ZapB; Cell division protein ZapB
    pfam11881
    Location:14831727
    SPAR_C; C-terminal domain of SPAR protein
  7. NM_001354288.2NP_001341217.1  signal-induced proliferation-associated 1-like protein 1 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR, lacks an alternate in-frame exon, uses an alternate in-frame splice site, compared to variant 1. The encoded isoform (3) is shorter than isoform 1. Variants 3, 6, 7, and 8 encode the same isoform (3).
    Source sequence(s)
    AC004900, AC004968, AC004974, AC005476, AF090989, AK122930, DA330003
    Consensus CDS
    CCDS61491.1
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17151770
    ZapB; Cell division protein ZapB
    pfam11881
    Location:14831727
    SPAR_C; C-terminal domain of SPAR protein
  8. NM_001354289.2NP_001341218.1  signal-induced proliferation-associated 1-like protein 1 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC004900, AC004968, AC004974, AC005476, AC005994, AF090989, DA330003
    Conserved Domains (4) summary
    cd00992
    Location:459529
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:135315
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:12211276
    ZapB; Cell division protein ZapB
    pfam11881
    Location:9891233
    SPAR_C; C-terminal domain of SPAR protein
  9. NM_001386936.1NP_001373865.1  signal-induced proliferation-associated 1-like protein 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10), as well as variant 2, encodes isoform 2.
    Source sequence(s)
    AC004900, AC004968, AC004974, AC005476
  10. NM_015556.4NP_056371.1  signal-induced proliferation-associated 1-like protein 1 isoform 1

    See identical proteins and their annotated locations for NP_056371.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1). Variants 1 and 5 encode the same isoform (1).
    Source sequence(s)
    AC004900, AC004968, AC004974, AC005476, AC005994, AF090990, DA330003
    Consensus CDS
    CCDS9807.1
    UniProtKB/Swiss-Prot
    O43166
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17371792
    ZapB; Cell division protein ZapB
    pfam11881
    Location:15041749
    SPAR_C; C-terminal domain of SPAR protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    71320418..71741209
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017021180.1XP_016876669.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O43166
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17371792
    ZapB; Cell division protein ZapB
    pfam11881
    Location:15041749
    SPAR_C; C-terminal domain of SPAR protein
  2. XM_017021177.1XP_016876666.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O43166
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17371792
    ZapB; Cell division protein ZapB
    pfam11881
    Location:15041749
    SPAR_C; C-terminal domain of SPAR protein
  3. XM_017021199.1XP_016876688.1  signal-induced proliferation-associated 1-like protein 1 isoform X7

  4. XM_017021197.1XP_016876686.1  signal-induced proliferation-associated 1-like protein 1 isoform X7

  5. XM_024449532.1XP_024305300.1  signal-induced proliferation-associated 1-like protein 1 isoform X3

    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17161771
    ZapB; Cell division protein ZapB
    pfam11881
    Location:14831728
    SPAR_C; C-terminal domain of SPAR protein
  6. XM_024449536.1XP_024305304.1  signal-induced proliferation-associated 1-like protein 1 isoform X8

    Conserved Domains (4) summary
    cd00992
    Location:459529
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:135315
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:12211276
    ZapB; Cell division protein ZapB
    pfam11881
    Location:9891233
    SPAR_C; C-terminal domain of SPAR protein
  7. XM_017021179.1XP_016876668.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O43166
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17371792
    ZapB; Cell division protein ZapB
    pfam11881
    Location:15041749
    SPAR_C; C-terminal domain of SPAR protein
  8. XM_024449529.1XP_024305297.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17371792
    ZapB; Cell division protein ZapB
    pfam11881
    Location:15041749
    SPAR_C; C-terminal domain of SPAR protein
  9. XM_017021198.1XP_016876687.1  signal-induced proliferation-associated 1-like protein 1 isoform X7

  10. XM_017021178.1XP_016876667.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O43166
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17371792
    ZapB; Cell division protein ZapB
    pfam11881
    Location:15041749
    SPAR_C; C-terminal domain of SPAR protein
  11. XM_024449530.1XP_024305298.1  signal-induced proliferation-associated 1-like protein 1 isoform X2

    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17361791
    ZapB; Cell division protein ZapB
    pfam11881
    Location:15041748
    SPAR_C; C-terminal domain of SPAR protein
  12. XM_011536635.3XP_011534937.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011534937.1

    UniProtKB/Swiss-Prot
    O43166
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17371792
    ZapB; Cell division protein ZapB
    pfam11881
    Location:15041749
    SPAR_C; C-terminal domain of SPAR protein
  13. XM_011536632.1XP_011534934.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011534934.1

    UniProtKB/Swiss-Prot
    O43166
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17371792
    ZapB; Cell division protein ZapB
    pfam11881
    Location:15041749
    SPAR_C; C-terminal domain of SPAR protein
  14. XM_011536630.1XP_011534932.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011534932.1

    UniProtKB/Swiss-Prot
    O43166
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17371792
    ZapB; Cell division protein ZapB
    pfam11881
    Location:15041749
    SPAR_C; C-terminal domain of SPAR protein
  15. XM_017021163.2XP_016876652.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O43166
    Related
    ENSP00000450832.1, ENST00000555818.5
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17371792
    ZapB; Cell division protein ZapB
    pfam11881
    Location:15041749
    SPAR_C; C-terminal domain of SPAR protein
  16. XM_011536631.1XP_011534933.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011534933.1

    UniProtKB/Swiss-Prot
    O43166
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17371792
    ZapB; Cell division protein ZapB
    pfam11881
    Location:15041749
    SPAR_C; C-terminal domain of SPAR protein
  17. XM_024449533.1XP_024305301.1  signal-induced proliferation-associated 1-like protein 1 isoform X4

    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:16881743
    ZapB; Cell division protein ZapB
    pfam11881
    Location:14551700
    SPAR_C; C-terminal domain of SPAR protein
  18. XM_024449534.1XP_024305302.1  signal-induced proliferation-associated 1-like protein 1 isoform X5

    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:16671722
    ZapB; Cell division protein ZapB
    pfam11881
    Location:14341679
    SPAR_C; C-terminal domain of SPAR protein
  19. XM_024449535.1XP_024305303.1  signal-induced proliferation-associated 1-like protein 1 isoform X6

    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:16661721
    ZapB; Cell division protein ZapB
    pfam11881
    Location:14341678
    SPAR_C; C-terminal domain of SPAR protein
  20. XM_005267516.4XP_005267573.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_005267573.1

    UniProtKB/Swiss-Prot
    O43166
    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17371792
    ZapB; Cell division protein ZapB
    pfam11881
    Location:15041749
    SPAR_C; C-terminal domain of SPAR protein
  21. XM_017021185.1XP_016876674.1  signal-induced proliferation-associated 1-like protein 1 isoform X2

    Conserved Domains (4) summary
    cd00992
    Location:9531023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:629809
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:17361791
    ZapB; Cell division protein ZapB
    pfam11881
    Location:15041748
    SPAR_C; C-terminal domain of SPAR protein
  22. XM_011536638.2XP_011534940.1  signal-induced proliferation-associated 1-like protein 1 isoform X9

    Conserved Domains (4) summary
    cd00992
    Location:428498
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:104284
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:12121267
    DUF904; Protein of unknown function (DUF904)
    pfam11881
    Location:9791224
    SPAR_C; C-terminal domain of SPAR protein
  23. XM_024449537.1XP_024305305.1  signal-induced proliferation-associated 1-like protein 1 isoform X10

    Related
    ENSP00000440682.1, ENST00000537413.5
    Conserved Domains (4) summary
    cd00992
    Location:428498
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam02145
    Location:104284
    Rap_GAP; Rap/ran-GAP
    pfam06005
    Location:11901245
    ZapB; Cell division protein ZapB
    pfam11881
    Location:9581202
    SPAR_C; C-terminal domain of SPAR protein
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