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Fev FEV transcription factor, ETS family member [ Mus musculus (house mouse) ]

Gene ID: 260298, updated on 17-Nov-2020

Summary

Official Symbol
Fevprovided by MGI
Official Full Name
FEV transcription factor, ETS family memberprovided by MGI
Primary source
MGI:MGI:2449712
See related
Ensembl:ENSMUSG00000055197
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pet; Pex; Pet1; Pex1; Pet-1; mPet-; mPet-1
Expression
Biased expression in duodenum adult (RPKM 1.0), testis adult (RPKM 1.0) and 10 other tissues See more
Orthologs

Genomic context

See Fev in Genome Data Viewer
Location:
1; 1 C4
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (74920660..74924632, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (74881501..74885473, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (74928083..74931982, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32275 Neighboring gene uncharacterized LOC118567754 Neighboring gene predicted gene 16582 Neighboring gene cyclin-dependent kinase 5, regulatory subunit 2 (p39) Neighboring gene crystallin, beta A2 Neighboring gene microRNA 375

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription activator activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
 
DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-binding transcription factor activity, RNA polymerase II-specific NAS
Non-traceable Author Statement
more info
PubMed 
RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
 
sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
nervous system development IEA
Inferred from Electronic Annotation
more info
 
neuron fate specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
neuron maturation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
regulation of serotonin biosynthetic process NAS
Non-traceable Author Statement
more info
PubMed 
regulation of serotonin uptake NAS
Non-traceable Author Statement
more info
PubMed 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription by RNA polymerase II NAS
Non-traceable Author Statement
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
neuronal cell body TAS
Traceable Author Statement
more info
PubMed 
nuclear speck ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
protein FEV
Names
ETS-domain transcription factor Pet-1
FEV (ETS oncogene family)
FEV (fifth Ewing variant)
PC12 ETS domain-containing transcription factor 1
PC12 ETS factor 1
pheochromocytoma 12 ETS (E26 transformation-specific)
plasmacytoma expressed transcript 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153111.2NP_694751.1  protein FEV

    See identical proteins and their annotated locations for NP_694751.1

    Status: VALIDATED

    Source sequence(s)
    AC139023, BC138435
    Consensus CDS
    CCDS15058.1
    UniProtKB/Swiss-Prot
    Q8QZW2
    Related
    ENSMUSP00000070878.3, ENSMUST00000068631.3
    Conserved Domains (1) summary
    smart00413
    Location:46131
    ETS; erythroblast transformation specific domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    74920660..74924632 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017320802.1XP_017176291.1  protein FEV isoform X1

    UniProtKB/TrEMBL
    E0CXR7
    Related
    ENSMUSP00000125067.1, ENSMUST00000159232.1
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