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FAM32A family with sequence similarity 32 member A [ Homo sapiens (human) ]

Gene ID: 26017, updated on 5-May-2024

Summary

Official Symbol
FAM32Aprovided by HGNC
Official Full Name
family with sequence similarity 32 member Aprovided by HGNC
Primary source
HGNC:HGNC:24563
See related
Ensembl:ENSG00000105058 MIM:614554; AllianceGenome:HGNC:24563
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OTAG12; OTAG-12
Summary
Enables RNA binding activity. Predicted to be involved in apoptotic process. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in duodenum (RPKM 31.4), small intestine (RPKM 30.9) and 25 other tissues See more
Orthologs
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Genomic context

See FAM32A in Genome Data Viewer
Location:
19p13.11
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (16185410..16192046)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (16319478..16326117)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (16296221..16302857)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene RAB8A, member RAS oncogene family Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14208 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14209 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:16253936-16254630 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14212 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14213 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10291 Neighboring gene hematopoietic SH2 domain containing Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14214 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14215 Neighboring gene Sharpr-MPRA regulatory region 5225 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14216 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:16293505-16294004 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:16295228-16295863 Neighboring gene calcium and integrin binding family member 3 Neighboring gene uncharacterized LOC124904646 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10292 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:16315239-16315388 Neighboring gene adaptor related protein complex 1 subunit mu 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:16334661-16335161 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:16362883-16363384 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:16363385-16363884 Neighboring gene KLF2-I enhancer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14218 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14219 Neighboring gene MPRA-validated peak3390 silencer Neighboring gene KLF2 divergent transcript Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14220 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10293 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14221 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:16435432-16436204

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
 
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleolus IDA
Inferred from Direct Assay
more info
 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
protein FAM32A
Names
ovarian tumor associated gene-12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014077.4NP_054796.1  protein FAM32A

    See identical proteins and their annotated locations for NP_054796.1

    Status: VALIDATED

    Source sequence(s)
    BC000639, BG749750
    Consensus CDS
    CCDS12341.1
    UniProtKB/Swiss-Prot
    Q9BT02, Q9Y421
    UniProtKB/TrEMBL
    B2R547
    Related
    ENSP00000263384.6, ENST00000263384.12

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    16185410..16192046
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    16319478..16326117
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)