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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029835.1 RefSeqGene
- Range
-
5058..127412
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001243286.2 → NP_001230215.1 nectin-3 isoform 2 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate splice site that results in a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (2) has a distinct and shorter C-terminus, compared to isoform 1.
- Source sequence(s)
-
AA555086, AC133477, AC137833, BC067808, BI464010
- Consensus CDS
-
CCDS58842.1
- UniProtKB/Swiss-Prot
-
Q9NQS3
- Related
- ENSP00000321514.3, ENST00000319792.7
- Conserved Domains (3) summary
-
- cd05887
Location:72 → 167
- Ig1_Nectin-3_like; First immunoglobulin (Ig) domain of nectin-3 (also known as poliovirus receptor related protein 3) and similar proteins
- smart00410
Location:64 → 166
- IG_like; Immunoglobulin like
- cl11960
Location:170 → 265
- Ig; Immunoglobulin domain
-
NM_001243288.2 → NP_001230217.1 nectin-3 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region, uses a distinct start codon, and has alternate exon structure in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (3) has distinct N- and C-termini and is shorter than isoform 1.
- Source sequence(s)
-
AC133436, AC133477, AK075105, BQ025085
- Consensus CDS
-
CCDS58843.1
- UniProtKB/Swiss-Prot
-
Q9NQS3
- Related
- ENSP00000420579.1, ENST00000493615.5
- Conserved Domains (4) summary
-
- cd05887
Location:49 → 144
- Ig1_Nectin-3_like; First immunoglobulin (Ig) domain of nectin-3 (also known as poliovirus receptor related protein 3) and similar proteins
- smart00410
Location:41 → 143
- IG_like; Immunoglobulin like
- pfam13927
Location:264 → 319
- Ig_3; Immunoglobulin domain
- cl11960
Location:147 → 242
- Ig; Immunoglobulin domain
-
NM_015480.3 → NP_056295.1 nectin-3 isoform 1 precursor
See identical proteins and their annotated locations for NP_056295.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AA555086, AC137833, AF282874, BI464010
- Consensus CDS
-
CCDS2957.1
- UniProtKB/Swiss-Prot
-
Q9NQS3
- Related
- ENSP00000418070.1, ENST00000485303.6
- Conserved Domains (5) summary
-
- cd05887
Location:72 → 167
- Ig1_Nectin-3_like; First immunoglobulin (Ig) domain of nectin-3 (also known as poliovirus receptor related protein 3) and similar proteins
- cd12087
Location:404 → 432
- TM_EGFR-like; Transmembrane domain of the Epidermal Growth Factor Receptor family of Protein Tyrosine Kinases
- smart00410
Location:64 → 166
- IG_like; Immunoglobulin like
- pfam13927
Location:287 → 342
- Ig_3; Immunoglobulin domain
- cl11960
Location:170 → 265
- Ig; Immunoglobulin domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p13 Primary Assembly
Genomic
-
NC_000003.12 Reference GRCh38.p13 Primary Assembly
- Range
-
111071764..111201444
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017006126.1 → XP_016861615.1 nectin-3 isoform X5
-
XM_017006123.1 → XP_016861612.1 nectin-3 isoform X2
-
XM_011512663.1 → XP_011510965.1 nectin-3 isoform X1
- Conserved Domains (5) summary
-
- cd05887
Location:103 → 198
- Ig1_Nectin-3_like; First immunoglobulin (Ig) domain of nectin-3 (also known as poliovirus receptor related protein 3) and similar proteins
- cd12087
Location:435 → 463
- TM_EGFR-like; Transmembrane domain of the Epidermal Growth Factor Receptor family of Protein Tyrosine Kinases
- smart00410
Location:95 → 197
- IG_like; Immunoglobulin like
- pfam13927
Location:318 → 373
- Ig_3; Immunoglobulin domain
- cl11960
Location:201 → 296
- Ig; Immunoglobulin domain
-
XM_017006125.1 → XP_016861614.1 nectin-3 isoform X4
-
XM_017006127.2 → XP_016861616.1 nectin-3 isoform X6
- Conserved Domains (4) summary
-
- cd12087
Location:192 → 220
- TM_EGFR-like; Transmembrane domain of the Epidermal Growth Factor Receptor family of Protein Tyrosine Kinases
- smart00410
Location:75 → 136
- IG_like; Immunoglobulin like
- pfam13927
Location:75 → 130
- Ig_3; Immunoglobulin domain
- cl11960
Location:1 → 53
- Ig; Immunoglobulin domain
-
XM_017006124.1 → XP_016861613.1 nectin-3 isoform X3
RNA
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XR_924122.2 RNA Sequence
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XR_002959508.1 RNA Sequence