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TAS2R30 taste 2 receptor member 30 [ Homo sapiens (human) ]

Gene ID: 259293, updated on 22-Sep-2022

Summary

Official Symbol
TAS2R30provided by HGNC
Official Full Name
taste 2 receptor member 30provided by HGNC
Primary source
HGNC:HGNC:19112
See related
Ensembl:ENSG00000256188 MIM:613963; AllianceGenome:HGNC:19112
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
T2R30; T2R47; TAS2R47
Summary
Enables bitter taste receptor activity. Involved in detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See TAS2R30 in Genome Data Viewer
Location:
12p13.2
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (11132958..11134644, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (11002322..11004010, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (11285557..11287243, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene PRH1-PRR4 readthrough Neighboring gene proline rich protein HaeIII subfamily 1 Neighboring gene PRH1-TAS2R14 readthrough Neighboring gene taste 2 receptor member 64 pseudogene Neighboring gene taste 2 receptor member 43 Neighboring gene taste 2 receptor member 18 pseudogene Neighboring gene small integral membrane protein 10 like 1

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables bitter taste receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables bitter taste receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IC
Inferred by Curator
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
taste receptor type 2 member 30
Names
taste receptor T2R47
taste receptor type 2 member 47
taste receptor, type 2, member 30
type 2 taste receptor member 30
type 2 taste receptor member 47

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001097643.2NP_001091112.1  taste receptor type 2 member 30

    See identical proteins and their annotated locations for NP_001091112.1

    Status: VALIDATED

    Source sequence(s)
    AC018630
    Consensus CDS
    CCDS53750.1
    UniProtKB/Swiss-Prot
    P59541, Q645X7
    Related
    ENSP00000444736.1, ENST00000539585.1
    Conserved Domains (1) summary
    pfam05296
    Location:1298
    TAS2R; Taste receptor protein (TAS2R)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    11132958..11134644 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NW_003571050.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    363612..365298 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

  1. NT_187658.1 Reference GRCh38.p14 ALT_REF_LOCI_2

    Range
    327990..329678 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    11002322..11004010 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)