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TAS2R45 taste 2 receptor member 45 [ Homo sapiens (human) ]

Gene ID: 259291, updated on 22-Sep-2022

Summary

Official Symbol
TAS2R45provided by HGNC
Official Full Name
taste 2 receptor member 45provided by HGNC
Primary source
HGNC:HGNC:18876
See related
MIM:613967; AllianceGenome:HGNC:18876
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GPR59; T2R45; ZG24P
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of taste. Is integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Annotation category: only annotated on alternate loci in reference assembly
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Genomic context

See TAS2R45 in Genome Data Viewer
Location:
12p13.2
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 12 (ALT_REF_LOCI_2) NT_187658.1 (291887..292786, complement)
110 current GRCh38.p14 (GCF_000001405.40) 12 (ALT_REF_LOCI_1) NW_003571050.1 (327525..328424, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (10966219..10967118, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 12 (PATCHES) NW_003571050.1 (327525..328424, complement)

NW_003571050.1Genomic Context describing neighboring genes Neighboring gene PRH1-PRR4 readthrough Neighboring gene proline rich protein HaeIII subfamily 1 Neighboring gene PRH1-TAS2R14 readthrough Neighboring gene taste 2 receptor member 43 Neighboring gene taste 2 receptor member 68 pseudogene Neighboring gene taste 2 receptor member 30 Neighboring gene taste 2 receptor member 18 pseudogene

NT_187658.1Genomic Context describing neighboring genes Neighboring gene PRH1-PRR4 readthrough Neighboring gene proline rich protein HaeIII subfamily 1 Neighboring gene PRH1-TAS2R14 readthrough Neighboring gene taste 2 receptor member 46 Neighboring gene taste 2 receptor member 68 pseudogene Neighboring gene taste 2 receptor member 30 Neighboring gene taste 2 receptor member 18 pseudogene

Genomic regions, transcripts, and products

General gene information

Markers

Clone Names

  • MGC119923, MGC119924, MGC119925

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
NOT enables bitter taste receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
taste receptor type 2 member 45
Names
G-protein coupled receptor 59
taste receptor, type 2, member 45

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_176886.2NP_795367.2  taste receptor type 2 member 45

    See identical proteins and their annotated locations for NP_795367.2

    Status: VALIDATED

    Source sequence(s)
    AC217021
    UniProtKB/TrEMBL
    A0A0J9YXD8
    Conserved Domains (1) summary
    pfam05296
    Location:1298
    TAS2R; Taste receptor protein (TAS2R)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NW_003571050.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    327525..328424 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

  1. NT_187658.1 Reference GRCh38.p14 ALT_REF_LOCI_2

    Range
    291887..292786 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    10966219..10967118 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)