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BOD1L1 biorientation of chromosomes in cell division 1 like 1 [ Homo sapiens (human) ]

Gene ID: 259282, updated on 9-Oct-2022

Summary

Official Symbol
BOD1L1provided by HGNC
Official Full Name
biorientation of chromosomes in cell division 1 like 1provided by HGNC
Primary source
HGNC:HGNC:31792
See related
Ensembl:ENSG00000038219 MIM:616746; AllianceGenome:HGNC:31792
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BOD1L; FAM44A
Summary
Predicted to enable protein phosphatase 2A binding activity and protein phosphatase inhibitor activity. Involved in cellular response to DNA damage stimulus and replication fork processing. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bone marrow (RPKM 8.2), testis (RPKM 7.4) and 25 other tissues See more
Orthologs
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Try the new Transcript table

Genomic context

See BOD1L1 in Genome Data Viewer
Location:
4p15.33
Exon count:
29
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (13568738..13627725, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (13548429..13607428, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (13570362..13629349, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene NK3 homeobox 2 Neighboring gene Sharpr-MPRA regulatory region 12016 Neighboring gene long intergenic non-protein coding RNA 1096 Neighboring gene ribosomal protein L21 pseudogene Neighboring gene microRNA 5091

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ33215, KIAA1327

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein phosphatase 2A binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein phosphatase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of Set1C/COMPASS complex IPI
Inferred from Physical Interaction
more info
PubMed 
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
part_of outer kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in spindle microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in spindle pole IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
biorientation of chromosomes in cell division protein 1-like 1
Names
biorientation of chromosomes in cell division 1-like
family with sequence similarity 44, member A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_148894.3NP_683692.2  biorientation of chromosomes in cell division protein 1-like 1

    See identical proteins and their annotated locations for NP_683692.2

    Status: VALIDATED

    Source sequence(s)
    AB037748, AC006445, AF528529, AK090534, BX648206
    Consensus CDS
    CCDS3411.2
    UniProtKB/Swiss-Prot
    Q8NFC6, Q9P2L9
    Related
    ENSP00000040738.5, ENST00000040738.10
    Conserved Domains (1) summary
    pfam05205
    Location:57150
    COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    13568738..13627725 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017008010.2XP_016863499.1  biorientation of chromosomes in cell division protein 1-like 1 isoform X8

  2. XM_005248151.4XP_005248208.1  biorientation of chromosomes in cell division protein 1-like 1 isoform X4

    Conserved Domains (1) summary
    pfam05205
    Location:57150
    COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1
  3. XM_017008009.2XP_016863498.1  biorientation of chromosomes in cell division protein 1-like 1 isoform X7

  4. XM_006713958.4XP_006714021.1  biorientation of chromosomes in cell division protein 1-like 1 isoform X2

    Conserved Domains (1) summary
    pfam05205
    Location:57150
    COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1
  5. XM_005248150.4XP_005248207.1  biorientation of chromosomes in cell division protein 1-like 1 isoform X3

    Related
    ENSP00000425492.2, ENST00000507943.2
    Conserved Domains (1) summary
    pfam05205
    Location:57150
    COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1
  6. XM_011513829.3XP_011512131.1  biorientation of chromosomes in cell division protein 1-like 1 isoform X6

    Conserved Domains (1) summary
    pfam05205
    Location:57150
    COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1
  7. XM_011513827.3XP_011512129.1  biorientation of chromosomes in cell division protein 1-like 1 isoform X1

    Conserved Domains (1) summary
    pfam05205
    Location:57150
    COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1
  8. XM_011513830.4XP_011512132.1  biorientation of chromosomes in cell division protein 1-like 1 isoform X9

    Conserved Domains (1) summary
    PTZ00121
    Location:12858
    PTZ00121; MAEBL; Provisional
  9. XM_047450037.1XP_047305993.1  biorientation of chromosomes in cell division protein 1-like 1 isoform X5

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    13548429..13607428 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)