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CNRIP1 cannabinoid receptor interacting protein 1 [ Homo sapiens (human) ]

Gene ID: 25927, updated on 12-Sep-2021

Summary

Official Symbol
CNRIP1provided by HGNC
Official Full Name
cannabinoid receptor interacting protein 1provided by HGNC
Primary source
HGNC:HGNC:24546
See related
Ensembl:ENSG00000119865 MIM:618538
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CRIP1; CRIP-1; C2orf32
Summary
This gene encodes a protein that interacts with the C-terminal tail of cannabinoid receptor 1. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2013]
Expression
Broad expression in brain (RPKM 31.7), ovary (RPKM 14.7) and 21 other tissues See more
Orthologs
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Genomic context

See CNRIP1 in Genome Data Viewer
Location:
2p14
Exon count:
5
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (68284171..68319949, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (68511303..68547081, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene partner of NOB1 homolog Neighboring gene VISTA enhancer hs2040 Neighboring gene protein phosphatase 3 regulatory subunit B, alpha Neighboring gene uncharacterized LOC107985892 Neighboring gene uncharacterized LOC102724389 Neighboring gene CRISPRi-validated cis-regulatory element chr2.2452

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
capsid gag The interaction of HIV-1 CA with human cellular cannabinoid receptor interacting protein 1 (CNRIP1) is identified by yeast two-hybrid screen PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp566K1924

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein C-terminus binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables type 1 cannabinoid receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables type 1 cannabinoid receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
CB1 cannabinoid receptor-interacting protein 1
Names
cannabinoid receptor CB1-interacting protein 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001111101.2NP_001104571.1  CB1 cannabinoid receptor-interacting protein 1 isoform CRIP1b

    See identical proteins and their annotated locations for NP_001104571.1

    Status: REVIEWED

    Source sequence(s)
    AC015969
    Consensus CDS
    CCDS46311.1
    UniProtKB/Swiss-Prot
    Q96F85
    Related
    ENSP00000386883.3, ENST00000409559.7
    Conserved Domains (1) summary
    pfam15043
    Location:4110
    CNRIP1; CB1 cannabinoid receptor-interacting protein 1
  2. NM_001371604.1NP_001358533.1  CB1 cannabinoid receptor-interacting protein 1 isoform CRIP1a

    Status: REVIEWED

    Source sequence(s)
    AC015969
    Conserved Domains (1) summary
    pfam15043
    Location:4158
    CNRIP1; CB1 cannabinoid receptor-interacting protein 1
  3. NM_001371605.1NP_001358534.1  CB1 cannabinoid receptor-interacting protein 1 isoform CRIP1a

    Status: REVIEWED

    Source sequence(s)
    AC015969
    Conserved Domains (1) summary
    pfam15043
    Location:4158
    CNRIP1; CB1 cannabinoid receptor-interacting protein 1
  4. NM_001371606.1NP_001358535.1  CB1 cannabinoid receptor-interacting protein 1 isoform CRIP1a

    Status: REVIEWED

    Source sequence(s)
    AC015969
    Conserved Domains (1) summary
    pfam15043
    Location:4158
    CNRIP1; CB1 cannabinoid receptor-interacting protein 1
  5. NM_001371607.1NP_001358536.1  CB1 cannabinoid receptor-interacting protein 1 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC015969
    Conserved Domains (1) summary
    pfam15043
    Location:26129
    CNRIP1; CB1 cannabinoid receptor-interacting protein 1
  6. NM_001371608.1NP_001358537.1  CB1 cannabinoid receptor-interacting protein 1 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC015969
    Conserved Domains (1) summary
    pfam15043
    Location:26129
    CNRIP1; CB1 cannabinoid receptor-interacting protein 1
  7. NM_015463.3NP_056278.1  CB1 cannabinoid receptor-interacting protein 1 isoform CRIP1a

    See identical proteins and their annotated locations for NP_056278.1

    Status: REVIEWED

    Source sequence(s)
    AC015969
    Consensus CDS
    CCDS1886.1
    UniProtKB/Swiss-Prot
    Q96F85
    Related
    ENSP00000263655.3, ENST00000263655.4
    Conserved Domains (1) summary
    pfam15043
    Location:4158
    CNRIP1; CB1 cannabinoid receptor-interacting protein 1

RNA

  1. NR_163969.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC015969
  2. NR_163970.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC015969
    Related
    ENST00000481714.1
  3. NR_163971.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC015969

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    68284171..68319949 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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