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MRGPRX1 MAS related GPR family member X1 [ Homo sapiens (human) ]

Gene ID: 259249, updated on 19-Sep-2021

Summary

Official Symbol
MRGPRX1provided by HGNC
Official Full Name
MAS related GPR family member X1provided by HGNC
Primary source
HGNC:HGNC:17962
See related
Ensembl:ENSG00000170255 MIM:607227
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GPCR; MGRG2; MRGX1; SNSR4
Orthologs
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Genomic context

See MRGPRX1 in Genome Data Viewer
Location:
11p15.1; 11
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (18933499..18939414, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (18955360..18956549, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene MAS related GPR family member X6, pseudogene Neighboring gene MAS related GPR family member X5, pseudogene Neighboring gene MAS related GPR family member X11, pseudogene Neighboring gene MAS related GPR family member X10, pseudogene

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transmembrane signaling receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in acute-phase response IEA
Inferred from Electronic Annotation
more info
 
involved_in cell surface receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in response to chloroquine IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in signal transduction IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cell surface IC
Inferred by Curator
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
mas-related G-protein coupled receptor member X1
Names
G protein-coupled receptor MRGX1
G protein-coupled receptor SNSR3
MAS-related GPR, member X1
Mas-related G protein-coupled receptor G2
sensory neuron-specific G-protein coupled receptor 3/4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001393578.1NP_001380507.1  mas-related G-protein coupled receptor member X1

    Status: VALIDATED

    Source sequence(s)
    AC023078
    Conserved Domains (1) summary
    cd15106
    Location:28299
    7tmA_MrgprX-like; primate-specific mas-related G protein-coupled receptor subtype X-like, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. NM_147199.4NP_671732.3  mas-related G-protein coupled receptor member X1

    See identical proteins and their annotated locations for NP_671732.3

    Status: VALIDATED

    Source sequence(s)
    AC023078
    Consensus CDS
    CCDS7846.1
    UniProtKB/Swiss-Prot
    Q96LB2
    UniProtKB/TrEMBL
    W8W3P5
    Related
    ENSP00000305766.3, ENST00000302797.4
    Conserved Domains (1) summary
    cd15106
    Location:28299
    7tmA_MrgprX-like; primate-specific mas-related G protein-coupled receptor subtype X-like, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    18933499..18939414 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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