Or52b4 olfactory receptor family 52 subfamily B member 4 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Or52b4provided by MGI
Official Full Name: olfactory receptor family 52 subfamily B member 4provided by MGI
Primary source: MGI:MGI:3030381
See related: Ensembl:ENSMUSG00000073979 AllianceGenome:MGI:3030381
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: MOR31-4; Olfr547
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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Genomic context

Location:: 7 E3; 7 54.75 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (102183956..102184895)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (102534749..102535688)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The receptive range of MOR31-4 is unique to its odorant space region.
Title: Molecular receptive range variation among mouse odorant receptors for aliphatic carboxylic acids.

Submit: New GeneRIF Correction

General gene information

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Markers

D7Mit218 (e-PCR), detects polymorphism
- UniSTS:131110

NoName (e-PCR)
- UniSTS:489510

NoName (e-PCR)
- UniSTS:495667

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables olfactory receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables olfactory receptor activity	IEA Inferred from Electronic Annotation more info
enables olfactory receptor activity	ISA Inferred from Sequence Alignment more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	ISA Inferred from Sequence Alignment more info	PubMed
involved_in cognition	IEA Inferred from Electronic Annotation more info
involved_in cognition	ISO Inferred from Sequence Orthology more info
involved_in detection of chemical stimulus involved in sensory perception of smell	IEA Inferred from Electronic Annotation more info
involved_in nervous system process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within sensory perception of smell	ISA Inferred from Sequence Alignment more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	ISA Inferred from Sequence Alignment more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: olfactory receptor 547

Names: GA_x6K02T2PBJ9-5256044-5256988; olfactory receptor MOR31-4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_147079.2 → NP_667290.2 olfactory receptor 547

Status: VALIDATED

Source sequence(s)

AC102535

Consensus CDS

CCDS40050.1

UniProtKB/TrEMBL

E9PXN3, E9Q536, Q7TRS7

Related

ENSMUSP00000095831.2, ENSMUST00000098229.3

Conserved Domains (2) summary

pfam00001
Location:43 → 294

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:33 → 309

7tm_4; Olfactory receptor