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Olfr139 olfactory receptor 139 [ Mus musculus (house mouse) ]

Gene ID: 259005, updated on 12-Aug-2019

Summary

Official Symbol
Olfr139provided by MGI
Official Full Name
olfactory receptor 139provided by MGI
Primary source
MGI:MGI:2177522
See related
Ensembl:ENSMUSG00000047444
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
M5; MOR255-2
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

Genomic context

See Olfr139 in Genome Data Viewer
Location:
11; 11 B4
Exon count:
1
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (74044325..74045272, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (73857827..73858774, complement)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene olfactory receptor 398 Neighboring gene olfactory receptor enhancer Crete Neighboring gene olfactory receptor 399 Neighboring gene zinc finger protein 616 Neighboring gene high mobility group box 2 pseudogene

Genomic regions, transcripts, and products

Pathways from BioSystems

  • Odorant GPCRs, organism-specific biosystem (from WikiPathways)
    Odorant GPCRs, organism-specific biosystem
    Odorant GPCRs
  • Olfactory transduction, organism-specific biosystem (from KEGG)
    Olfactory transduction, organism-specific biosystemWithin the compact cilia of the olfactory receptor neurons (ORNs) a cascade of enzymatic activity transduces the binding of an odorant molecule to a receptor into an electrical signal that can be tra...
  • Olfactory transduction, conserved biosystem (from KEGG)
    Olfactory transduction, conserved biosystemWithin the compact cilia of the olfactory receptor neurons (ORNs) a cascade of enzymatic activity transduces the binding of an odorant molecule to a receptor into an electrical signal that can be tra...

General gene information

Markers

Clone Names

  • MGC123735, MGC123736

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
PubMed 
Process Evidence Code Pubs
G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
PubMed 
response to stimulus IEA
Inferred from Electronic Annotation
more info
 
sensory perception of smell ISA
Inferred from Sequence Alignment
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane ISA
Inferred from Sequence Alignment
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 139
Names
GA_x6K02T2P1NL-4202012-4201065
odorant receptor M5
olfactory receptor 1
olfactory receptor 255-2
olfactory receptor MOR255-2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_147003.1NP_667214.1  olfactory receptor 139

    See identical proteins and their annotated locations for NP_667214.1

    Status: VALIDATED

    Source sequence(s)
    AY073085
    Consensus CDS
    CCDS25023.1
    UniProtKB/Swiss-Prot
    Q60891
    Related
    ENSMUSP00000049558.1, ENSMUST00000050678.1
    Conserved Domains (2) summary
    pfam00001
    Location:44293
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:34311
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p6 C57BL/6J

    Range
    74044325..74045272 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p6 NOD/MrkTac

Genomic

  1. NT_166317.2 Reference GRCm38.p6 NOD/MrkTac

    Range
    1136035..1136982 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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