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SPEF1 sperm flagellar 1 [ Homo sapiens (human) ]

Gene ID: 25876, updated on 15-Jun-2019

Summary

Official Symbol
SPEF1provided by HGNC
Official Full Name
sperm flagellar 1provided by HGNC
Primary source
HGNC:HGNC:15874
See related
Ensembl:ENSG00000101222 MIM:610674
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CLAMP; SPEF1A; C20orf28
Expression
Biased expression in testis (RPKM 4.6), brain (RPKM 1.1) and 4 other tissues See more
Orthologs

Genomic context

See SPEF1 in Genome Data Viewer
Location:
20p13
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 20 NC_000020.11 (3777504..3781466, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (3758151..3762113, complement)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene heat shock protein family A (Hsp70) member 12B Neighboring gene chromosome 20 open reading frame 27 Neighboring gene centromere protein B Neighboring gene cell division cycle 25B

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp434I114

Gene Ontology Provided by GOA

Function Evidence Code Pubs
microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule binding ISS
Inferred from Sequence or Structural Similarity
more info
 
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
cell migration ISS
Inferred from Sequence or Structural Similarity
more info
 
cilium-dependent cell motility IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of microtubule depolymerization ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
axoneme IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
axoneme ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular_component ND
No biological Data available
more info
 
motile cilium IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
sperm flagellar protein 1
Names
calponin-homology and microtubule-associated protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015417.5NP_056232.2  sperm flagellar protein 1

    See identical proteins and their annotated locations for NP_056232.2

    Status: VALIDATED

    Source sequence(s)
    AI925267, AL040853, AL080154, DB030684, DB033051
    Consensus CDS
    CCDS13063.2
    UniProtKB/Swiss-Prot
    Q9Y4P9
    Related
    ENSP00000369080.3, ENST00000379756.3
    Conserved Domains (1) summary
    pfam06294
    Location:14104
    CH_2; CH-like domain in sperm protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p13 Primary Assembly

    Range
    3777504..3781448 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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