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Olfr424 olfactory receptor 424 [ Mus musculus (house mouse) ]

Gene ID: 258716, updated on 23-Jun-2021

Summary

Official Symbol
Olfr424provided by MGI
Official Full Name
olfactory receptor 424provided by MGI
Primary source
MGI:MGI:3030258
See related
Ensembl:ENSMUSG00000051528
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MOR105; MOR105-2
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See Olfr424 in Genome Data Viewer
Location:
1; 1 H3
Exon count:
1
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (173964312..173965259)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (174136746..174137693)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (176066877..176067824)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor 1566, pseudogene 1 Neighboring gene olfactory receptor 231 Neighboring gene olfactory receptor 258, pseudogene 1 Neighboring gene olfactory receptor 421, pseudogene 1

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Clone Names

  • MGC123722, MGC123723

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables odorant binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
PubMed 
Component Evidence Code Pubs
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of membrane ISA
Inferred from Sequence Alignment
more info
PubMed 

General protein information

Preferred Names
olfactory receptor 424
Names
GA_x6K02T2P20D-21025190-21024243
olfactory receptor MOR105-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146721.2NP_666932.2  olfactory receptor 424

    Status: VALIDATED

    Source sequence(s)
    AC113483, BC104096
    Consensus CDS
    CCDS15538.1
    UniProtKB/TrEMBL
    E9Q0Q2, Q8VFZ1
    Related
    ENSMUSP00000054305.4, ENSMUST00000053941.4
    Conserved Domains (2) summary
    pfam00001
    Location:41289
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:35305
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    173964312..173965259
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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