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TMEM59L transmembrane protein 59 like [ Homo sapiens (human) ]

Gene ID: 25789, updated on 18-Aug-2020

Summary

Official Symbol
TMEM59Lprovided by HGNC
Official Full Name
transmembrane protein 59 likeprovided by HGNC
Primary source
HGNC:HGNC:13237
See related
Ensembl:ENSG00000105696 MIM:617096
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BSMAP; C19orf4
Summary
This gene encodes a predicted type-I membrane glycoprotein. The encoded protein may play a role in functioning of the central nervous system. [provided by RefSeq, Jul 2008]
Expression
Biased expression in brain (RPKM 110.1) and adrenal (RPKM 8.4) See more
Orthologs

Genomic context

See TMEM59L in Genome Data Viewer
Location:
19p13.11
Exon count:
7
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (18612870..18621040)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (18723682..18731849)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene required for excision 1-B domain containing Neighboring gene Sharpr-MPRA regulatory region 11645 Neighboring gene cytokine receptor like factor 1 Neighboring gene RNA, 7SL, cytoplasmic 155, pseudogene Neighboring gene kelch like family member 26

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane TAS
Traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
transmembrane protein 59-like
Names
brain-specific membrane-anchored protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012109.3NP_036241.1  transmembrane protein 59-like precursor

    See identical proteins and their annotated locations for NP_036241.1

    Status: REVIEWED

    Source sequence(s)
    AC003112, AF186264, BC010446, BI752768
    Consensus CDS
    CCDS12383.1
    UniProtKB/Swiss-Prot
    Q9UK28
    UniProtKB/TrEMBL
    A0A024R7L4
    Related
    ENSP00000262817.3, ENST00000262817.8
    Conserved Domains (1) summary
    pfam12280
    Location:79284
    BSMAP; Brain specific membrane anchored protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    18612870..18621040
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_002958292.1 RNA Sequence

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