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GAGE6 G antigen 6 [ Homo sapiens (human) ]

Gene ID: 2578, updated on 9-Jun-2019

Summary

Official Symbol
GAGE6provided by HGNC
Official Full Name
G antigen 6provided by HGNC
Primary source
HGNC:HGNC:4103
See related
MIM:300599
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT4.6
Summary
This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YYWPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008]
Annotation information
not in current annotation release

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

General protein information

Preferred Names
G antigen 6
Names
GAGE-6
cancer/testis antigen 4.6
cancer/testis antigen family 4, member 6

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001476.1NP_001467.1  G antigen 6

    See identical proteins and their annotated locations for NP_001467.1

    Status: REVIEWED

    Source sequence(s)
    U19147
    UniProtKB/Swiss-Prot
    Q13070
    Conserved Domains (1) summary
    pfam05831
    Location:1114
    GAGE; GAGE protein
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