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C22orf31 chromosome 22 open reading frame 31 [ Homo sapiens (human) ]

Gene ID: 25770, updated on 5-Aug-2022

Summary

Official Symbol
C22orf31provided by HGNC
Official Full Name
chromosome 22 open reading frame 31provided by HGNC
Primary source
HGNC:HGNC:26931
See related
Ensembl:ENSG00000100249 AllianceGenome:HGNC:26931
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HS747E2A; bK747E2.1
Expression
Biased expression in testis (RPKM 2.6), brain (RPKM 0.2) and 1 other tissue See more
Orthologs
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Genomic context

See C22orf31 in Genome Data Viewer
Location:
22q12.1
Exon count:
6
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (29058672..29073943, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (29519948..29535171, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (29454660..29469931, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene zinc and ring finger 3 Neighboring gene ZNRF3 antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 3696 Neighboring gene kringle containing transmembrane protein 1 Neighboring gene RNA, U6 small nuclear 810, pseudogene Neighboring gene uncharacterized LOC101929638 Neighboring gene RNA, U6 small nuclear 1219, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

EBI GWAS Catalog

Description
Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

General protein information

Preferred Names
uncharacterized protein C22orf31

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001386866.1NP_001373795.1  uncharacterized protein C22orf31 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL021393
    Conserved Domains (1) summary
    pfam15578
    Location:1221
    DUF4662; Domain of unknown function (DUF4662)
  2. NM_015370.2NP_056185.1  uncharacterized protein C22orf31 isoform 1

    See identical proteins and their annotated locations for NP_056185.1

    Status: VALIDATED

    Source sequence(s)
    AL021393
    Consensus CDS
    CCDS13848.1
    UniProtKB/Swiss-Prot
    A0AV97, O95567
    Related
    ENSP00000216071.4, ENST00000216071.5
    Conserved Domains (1) summary
    pfam15578
    Location:2262
    DUF4662; Domain of unknown function (DUF4662)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    29058672..29073943 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017028741.2XP_016884230.1  uncharacterized protein C22orf31 isoform X1

    Conserved Domains (1) summary
    pfam15578
    Location:1221
    DUF4662; Domain of unknown function (DUF4662)
  2. XM_005261491.3XP_005261548.1  uncharacterized protein C22orf31 isoform X2

    Conserved Domains (1) summary
    pfam15578
    Location:40158
    DUF4662; Domain of unknown function (DUF4662)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    29519948..29535171 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)