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Scg5 secretogranin V [ Rattus norvegicus (Norway rat) ]

Gene ID: 25719, updated on 19-Mar-2019

Summary

Official Symbol
Scg5provided by RGD
Official Full Name
secretogranin Vprovided by RGD
Primary source
RGD:3669
See related
Ensembl:ENSRNOG00000007542
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
7B2; Sgne1
Summary
mouse homolog plays a role in the transport and activation of proprotein convertase-2 (PC2); may regulate hormone secretion [RGD, Feb 2006]
Expression
Restricted expression toward (RPKM 1374.1) See more
Orthologs

Genomic context

See Scg5 in Genome Data Viewer
Location:
3q35
Exon count:
6
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (105235065..105279475, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 3 NC_005102.3 (111811718..111856212, complement)

Chromosome 3 - NC_005102.4Genomic Context describing neighboring genes Neighboring gene similar to sorbitol dehydrogenase 1 Neighboring gene gremlin 1, DAN family BMP antagonist Neighboring gene Rho GTPase activating protein 11A Neighboring gene uncharacterized LOC108350437 Neighboring gene 60S ribosomal protein L17 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enzyme inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
enzyme inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
enzyme inhibitor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
unfolded protein binding IEA
Inferred from Electronic Annotation
more info
 
unfolded protein binding ISO
Inferred from Sequence Orthology
more info
 
unfolded protein binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 
intracellular protein transport ISO
Inferred from Sequence Orthology
more info
 
intracellular protein transport ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 
neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
 
peptide hormone processing IEA
Inferred from Electronic Annotation
more info
 
peptide hormone processing ISO
Inferred from Sequence Orthology
more info
 
peptide hormone processing ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of hormone secretion IEA
Inferred from Electronic Annotation
more info
 
regulation of hormone secretion ISO
Inferred from Sequence Orthology
more info
 
regulation of hormone secretion ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
secretory granule IEA
Inferred from Electronic Annotation
more info
 
secretory granule ISO
Inferred from Sequence Orthology
more info
 
secretory granule ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
neuroendocrine protein 7B2
Names
Secretory granule neuroendocrine, protein 1 (7B2 protein)
secretogranin V (7B2 protein)
secretogranin-5
secretory granule endocrine protein I
secretory granule neuroendocrine protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013175.3NP_037307.1  neuroendocrine protein 7B2 precursor

    See identical proteins and their annotated locations for NP_037307.1

    Status: PROVISIONAL

    Source sequence(s)
    BC061560
    UniProtKB/Swiss-Prot
    P27682
    Related
    ENSRNOP00000010679.5, ENSRNOT00000010679.6
    Conserved Domains (1) summary
    pfam05281
    Location:22197
    Secretogranin_V; Neuroendocrine protein 7B2 precursor (Secretogranin V)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005102.4 Reference Rnor_6.0 Primary Assembly

    Range
    105235065..105279475 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006234701.3XP_006234763.1  neuroendocrine protein 7B2 isoform X1

    Conserved Domains (1) summary
    pfam05281
    Location:22196
    Secretogranin_V; Neuroendocrine protein 7B2 precursor (Secretogranin V)

Alternate Rn_Celera

Genomic

  1. AC_000071.1 Alternate Rn_Celera

    Range
    99515552..99558902 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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