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Myf6 myogenic factor 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 25714, updated on 18-Apr-2019

Summary

Official Symbol
Myf6provided by RGD
Official Full Name
myogenic factor 6provided by RGD
Primary source
RGD:3134
See related
Ensembl:ENSRNOG00000004878
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
MRF4AA
Summary
DNA binding protein; involved in muscle differentiation [RGD, Feb 2006]
Expression
Restricted expression toward (RPKM 474.3) See more
Orthologs

Genomic context

See Myf6 in Genome Data Viewer
Location:
7q21
Exon count:
3
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (49739643..49741490, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 7 NC_005106.3 (49749554..49751448, complement)

Chromosome 7 - NC_005106.4Genomic Context describing neighboring genes Neighboring gene protein lin-7 homolog A-like Neighboring gene myogenic factor 5 Neighboring gene protein tyrosine phosphatase, receptor type, Q Neighboring gene uncharacterized LOC103690159 Neighboring gene uncharacterized LOC102549995

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-binding transcription activator activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
PubMed 
RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
molecular_function ND
No biological Data available
more info
 
protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
muscle tissue morphogenesis IEA
Inferred from Electronic Annotation
more info
 
muscle tissue morphogenesis ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of myoblast differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of myoblast fusion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of skeletal muscle fiber development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
PubMed 
skeletal muscle cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
skeletal muscle cell differentiation ISO
Inferred from Sequence Orthology
more info
PubMed 
skeletal muscle tissue development ISO
Inferred from Sequence Orthology
more info
PubMed 
skeletal muscle tissue regeneration IMP
Inferred from Mutant Phenotype
more info
PubMed 
somitogenesis IEA
Inferred from Electronic Annotation
more info
 
somitogenesis ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
myogenic factor 6
Names
Myogenic factor 6 (herculin)
muscle-specific regulatory factor 4
myf-6

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013172.2NP_037304.1  myogenic factor 6

    See identical proteins and their annotated locations for NP_037304.1

    Status: PROVISIONAL

    Source sequence(s)
    M27151
    UniProtKB/Swiss-Prot
    P19335
    Related
    ENSRNOP00000006523.4, ENSRNOT00000006523.5
    Conserved Domains (2) summary
    pfam00010
    Location:94145
    HLH; Helix-loop-helix DNA-binding domain
    pfam01586
    Location:393
    Basic; Myogenic Basic domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005106.4 Reference Rnor_6.0 Primary Assembly

    Range
    49739643..49741490 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000075.1 Alternate Rn_Celera

    Range
    39685604..39687449 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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