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OR51F1 olfactory receptor family 51 subfamily F member 1 [ Homo sapiens (human) ]

Gene ID: 256892, updated on 26-Oct-2022

Summary

Official Symbol
OR51F1provided by HGNC
Official Full Name
olfactory receptor family 51 subfamily F member 1provided by HGNC
Primary source
HGNC:HGNC:15196
See related
Ensembl:ENSG00000280021 AllianceGenome:HGNC:15196
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR11-21; OR51F1P
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015]
Annotation information
Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
Orthologs
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Genomic context

See OR51F1 in Genome Data Viewer
Location:
11p15.4
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (4768979..4769938, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (4834501..4835460, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (4790209..4791168, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene matrix metallopeptidase 26 Neighboring gene small nucleolar RNA SNORA62/SNORA6 family Neighboring gene olfactory receptor family 51 subfamily F member 4 pseudogene Neighboring gene olfactory receptor family 51 subfamily N member 1 pseudogene Neighboring gene olfactory receptor family 52 subfamily Y member 1 pseudogene

Genomic regions, transcripts, and products

Phenotypes

EBI GWAS Catalog

Description
Imputation-based meta-analysis of severe malaria in three African populations.
EBI GWAS Catalog

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
olfactory receptor 51F1
Names
olfactory receptor OR11-21 pseudogene
olfactory receptor, family 51, subfamily F, member 1 pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004752.2NP_001004752.2  olfactory receptor 51F1

    Status: VALIDATED

    Source sequence(s)
    AC103710
    Consensus CDS
    CCDS31359.1
    UniProtKB/Swiss-Prot
    A6NGY5
    Related
    ENSP00000485387.2, ENST00000624103.2

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    4768979..4769938 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    4834501..4835460 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)