Format

Send to:

Choose Destination

C10orf67 chromosome 10 open reading frame 67 [ Homo sapiens (human) ]

Gene ID: 256815, updated on 22-Aug-2020

Summary

Official Symbol
C10orf67provided by HGNC
Official Full Name
chromosome 10 open reading frame 67provided by HGNC
Primary source
HGNC:HGNC:28716
See related
Ensembl:ENSG00000179133
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C10orf115; LINC01552
Expression
Biased expression in testis (RPKM 1.5), lung (RPKM 0.5) and 2 other tissues See more
Orthologs

Genomic context

See C10orf67 in Genome Data Viewer
Location:
10p12.2
Exon count:
24
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (23201916..23345216, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (23605520..23633772, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta pseudogene 3 Neighboring gene pancreas associated transcription factor 1a Neighboring gene uncharacterized LOC105376453 Neighboring gene MIR1254-2-OTUD1 intergenic CAGE-defined monocyte enhancer Neighboring gene OTU deubiquitinase 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
Genome-wide association analysis in sarcoidosis and Crohn's disease unravels a common susceptibility locus on 10p12.2.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC46732

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
uncharacterized protein C10orf67, mitochondrial
Names
long intergenic non-protein coding RNA 1552

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001351306.2NP_001338235.1  uncharacterized protein C10orf67, mitochondrial isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL592296, AL606469, BC035732
    Related
    ENSP00000497121.1, ENST00000649478.1
    Conserved Domains (1) summary
    pfam15821
    Location:70179
    DUF4709; Domain of unknown function (DUF4709)
  2. NM_001365862.2NP_001352791.1  uncharacterized protein C10orf67, mitochondrial isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AL139281, AL592296, AL606469
    Conserved Domains (3) summary
    pfam15821
    Location:70179
    DUF4709; Domain of unknown function (DUF4709)
    pfam15852
    Location:458544
    DUF4724; Domain of unknown function (DUF4724)
    cl25732
    Location:208439
    SMC_N; RecF/RecN/SMC N terminal domain
  3. NM_001371909.1NP_001358838.1  uncharacterized protein C10orf67, mitochondrial isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL139281, AL592296, AL606469
    Related
    ENSP00000490528.2, ENST00000636213.3
  4. NM_153714.3NP_714925.2  uncharacterized protein C10orf67, mitochondrial isoform 1

    See identical proteins and their annotated locations for NP_714925.2

    Status: VALIDATED

    Source sequence(s)
    AL592296, AL606469
    Consensus CDS
    CCDS44365.1
    UniProtKB/Swiss-Prot
    Q8IYJ2
    Related
    ENSP00000501139.1, ENST00000673651.1
    Conserved Domains (1) summary
    pfam15821
    Location:70179
    DUF4709; Domain of unknown function (DUF4709)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    23201916..23345216 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017016031.1XP_016871520.1  uncharacterized protein C10orf67, mitochondrial isoform X2

  2. XM_011519443.1XP_011517745.1  uncharacterized protein C10orf67, mitochondrial isoform X6

    Conserved Domains (1) summary
    pfam15852
    Location:184270
    DUF4724; Domain of unknown function (DUF4724)
  3. XM_011519440.1XP_011517742.1  uncharacterized protein C10orf67, mitochondrial isoform X3

    Conserved Domains (2) summary
    pfam13118
    Location:266317
    DUF3972; Protein of unknown function (DUF3972)
    pfam15821
    Location:70179
    DUF4709; Domain of unknown function (DUF4709)
  4. XM_011519441.1XP_011517743.1  uncharacterized protein C10orf67, mitochondrial isoform X4

    Conserved Domains (2) summary
    pfam15821
    Location:70179
    DUF4709; Domain of unknown function (DUF4709)
    cl19548
    Location:100405
    DUF515; Protein of unknown function (DUF515)
  5. XM_011519442.2XP_011517744.1  uncharacterized protein C10orf67, mitochondrial isoform X5

    Conserved Domains (2) summary
    pfam13118
    Location:266317
    DUF3972; Protein of unknown function (DUF3972)
    pfam15821
    Location:70179
    DUF4709; Domain of unknown function (DUF4709)
  6. XM_011519445.2XP_011517747.1  uncharacterized protein C10orf67, mitochondrial isoform X7

    Conserved Domains (1) summary
    pfam15821
    Location:70179
    DUF4709; Domain of unknown function (DUF4709)
  7. XM_011519446.1XP_011517748.1  uncharacterized protein C10orf67, mitochondrial isoform X8

    See identical proteins and their annotated locations for XP_011517748.1

    Conserved Domains (1) summary
    pfam15821
    Location:70179
    DUF4709; Domain of unknown function (DUF4709)

RNA

  1. XR_001747077.2 RNA Sequence

    Related
    ENST00000376501.7
  2. XR_930487.1 RNA Sequence

  3. XR_930488.1 RNA Sequence

Support Center