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LYSMD2 LysM domain containing 2 [ Homo sapiens (human) ]

Gene ID: 256586, updated on 11-Sep-2019

Summary

Official Symbol
LYSMD2provided by HGNC
Official Full Name
LysM domain containing 2provided by HGNC
Primary source
HGNC:HGNC:28571
See related
Ensembl:ENSG00000140280
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in brain (RPKM 8.4), lymph node (RPKM 8.3) and 25 other tissues See more
Orthologs

Genomic context

See LYSMD2 in Genome Data Viewer
Location:
15q21.2
Exon count:
5
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (51723011..51751453, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (52015261..52043650, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105370816 Neighboring gene secretogranin III Neighboring gene tropomodulin 2 Neighboring gene tropomodulin 3 Neighboring gene UTP6, small subunit (SSU) processome component, homolog (yeast) pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC35274, DKFZp686I2243

General protein information

Preferred Names
lysM and putative peptidoglycan-binding domain-containing protein 2
Names
LysM, putative peptidoglycan-binding, domain containing 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001143917.1NP_001137389.1  lysM and putative peptidoglycan-binding domain-containing protein 2 isoform 2

    See identical proteins and their annotated locations for NP_001137389.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region because it has a different first exon, compared to variant 1. These differences result in translation initiation from a downstream in-frame start codon and a protein (isoform 2) with a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    BC022075, BC033515, BQ446302
    Consensus CDS
    CCDS45259.1
    UniProtKB/Swiss-Prot
    Q8IV50
    Related
    ENSP00000410424.2, ENST00000454181.6
  2. NM_001363969.1NP_001350898.1  lysM and putative peptidoglycan-binding domain-containing protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC026770
    Consensus CDS
    CCDS45259.1
    Related
    ENSP00000453933.1, ENST00000560491.2
  3. NM_153374.3NP_699205.1  lysM and putative peptidoglycan-binding domain-containing protein 2 isoform 1

    See identical proteins and their annotated locations for NP_699205.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC026770, BC033515, BQ446302
    Consensus CDS
    CCDS10143.1
    UniProtKB/Swiss-Prot
    Q8IV50
    Related
    ENSP00000267838.3, ENST00000267838.7
    Conserved Domains (1) summary
    cd00118
    Location:71115
    LysM; Lysine Motif is a small domain involved in binding peptidoglycan

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    51723011..51751453 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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