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CCDC110 coiled-coil domain containing 110 [ Homo sapiens (human) ]

Gene ID: 256309, updated on 4-Oct-2020

Summary

Official Symbol
CCDC110provided by HGNC
Official Full Name
coiled-coil domain containing 110provided by HGNC
Primary source
HGNC:HGNC:28504
See related
Ensembl:ENSG00000168491 MIM:609488
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT52; KMHN1; KM-HN-1
Expression
Restricted expression toward testis (RPKM 45.3) See more
Orthologs

Genomic context

See CCDC110 in Genome Data Viewer
Location:
4q35.1
Exon count:
13
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (185445182..185471752, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (186366336..186392913, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986206 Neighboring gene LRP2 binding protein Neighboring gene ankyrin repeat domain 37 Neighboring gene UFM1 specific peptidase 2 Neighboring gene chromosome 4 open reading frame 47 Neighboring gene uncharacterized LOC105377590 Neighboring gene PDZ and LIM domain 3 Neighboring gene VISTA enhancer hs2502

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC33607

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
coiled-coil domain-containing protein 110
Names
cancer/testis antigen 52
cancer/testis antigen KM-HN-1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145411.2NP_001138883.1  coiled-coil domain-containing protein 110 isoform b

    See identical proteins and their annotated locations for NP_001138883.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting protein (isoform b) is shorter compared to isoform a.
    Source sequence(s)
    AC106897
    Consensus CDS
    CCDS47170.1
    UniProtKB/Swiss-Prot
    Q8TBZ0
    Related
    ENSP00000377172.3, ENST00000393540.7
    Conserved Domains (1) summary
    cl25732
    Location:399734
    SMC_N; RecF/RecN/SMC N terminal domain
  2. NM_152775.4NP_689988.1  coiled-coil domain-containing protein 110 isoform a

    See identical proteins and their annotated locations for NP_689988.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AC106897
    Consensus CDS
    CCDS3843.1
    UniProtKB/Swiss-Prot
    Q8TBZ0
    Related
    ENSP00000306776.3, ENST00000307588.8
    Conserved Domains (1) summary
    cl25732
    Location:436771
    SMC_N; RecF/RecN/SMC N terminal domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    185445182..185471752 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017007988.1XP_016863477.1  coiled-coil domain-containing protein 110 isoform X6

  2. XM_006714172.2XP_006714235.1  coiled-coil domain-containing protein 110 isoform X3

    Conserved Domains (1) summary
    pfam09728
    Location:441739
    Taxilin; Myosin-like coiled-coil protein
  3. XM_011531829.2XP_011530131.1  coiled-coil domain-containing protein 110 isoform X5

    Conserved Domains (1) summary
    pfam09728
    Location:371669
    Taxilin; Myosin-like coiled-coil protein
  4. XM_011531828.2XP_011530130.1  coiled-coil domain-containing protein 110 isoform X2

    Conserved Domains (1) summary
    pfam09728
    Location:421719
    Taxilin; Myosin-like coiled-coil protein
  5. XM_017007987.1XP_016863476.1  coiled-coil domain-containing protein 110 isoform X5

    Conserved Domains (1) summary
    pfam09728
    Location:371669
    Taxilin; Myosin-like coiled-coil protein
  6. XM_011531827.2XP_011530129.1  coiled-coil domain-containing protein 110 isoform X1

    Conserved Domains (1) summary
    pfam09728
    Location:441739
    Taxilin; Myosin-like coiled-coil protein
  7. XM_005262891.3XP_005262948.1  coiled-coil domain-containing protein 110 isoform X4

    UniProtKB/TrEMBL
    E7EUS2
    Related
    ENSP00000427246.1, ENST00000510617.5
    Conserved Domains (1) summary
    pfam09728
    Location:441739
    Taxilin; Myosin-like coiled-coil protein

RNA

  1. XR_002959722.1 RNA Sequence

  2. XR_427540.3 RNA Sequence

    Related
    ENST00000651260.1
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