U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

INAFM1 InaF motif containing 1 [ Homo sapiens (human) ]

Gene ID: 255783, updated on 10-Dec-2024

Summary

Official Symbol
INAFM1provided by HGNC
Official Full Name
InaF motif containing 1provided by HGNC
Primary source
HGNC:HGNC:27406
See related
Ensembl:ENSG00000257704 AllianceGenome:HGNC:27406
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRR24
Summary
Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
Expression
Ubiquitous expression in adrenal (RPKM 12.5), endometrium (RPKM 9.8) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See INAFM1 in Genome Data Viewer
Location:
19q13.32
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (47274423..47275723)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (50097601..50101037)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (47777680..47778980)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:47730339-47731281 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10841 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10842 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10843 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14861 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:47735673-47736296 Neighboring gene BCL2 binding component 3 Neighboring gene microRNA 3190 Neighboring gene microRNA 3191 Neighboring gene uncharacterized LOC124904731 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10844 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:47744377-47745178 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14863 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14864 Neighboring gene CRISPRi-validated cis-regulatory element chr19.5064 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:47759131-47760040 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10848 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10849 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:47769923-47770422 Neighboring gene coiled-coil domain containing 9 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10850 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10851 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10852 Neighboring gene CRISPRi-validated cis-regulatory element chr19.5070 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:47793125-47793976 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:47818477-47818672 Neighboring gene Sharpr-MPRA regulatory region 10427 Neighboring gene complement C5a receptor 1 Neighboring gene Sharpr-MPRA regulatory region 4678 Neighboring gene complement C5a receptor 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General protein information

Preferred Names
putative transmembrane protein INAFM1
Names
inaF-motif-containing protein 1
proline rich 24
proline-rich protein 24

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178511.6NP_848606.3  putative transmembrane protein INAFM1

    See identical proteins and their annotated locations for NP_848606.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) is intronless and encodes a 195aa protein.
    Source sequence(s)
    BC022076, BC064510
    Consensus CDS
    CCDS46131.1
    UniProtKB/Swiss-Prot
    C9JVW0
    Related
    ENSP00000447679.1, ENST00000552360.4
    Conserved Domains (1) summary
    pfam15018
    Location:2558
    InaF-motif; TRP-interacting helix

RNA

  1. NR_037675.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an internal segment and does not have an in-frame coding region, as compared to variant 1. The transcript does not appear to encode a protein.
    Source sequence(s)
    BC064510, BQ708656

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    47274423..47275723
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    50097601..50101037
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054320448.1XP_054176423.1  putative transmembrane protein INAFM1 isoform X1