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Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta [ Rattus norvegicus (Norway rat) ]

Gene ID: 25578, updated on 26-Jan-2021

Summary

Official Symbol
Ywhazprovided by RGD
Official Full Name
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zetaprovided by RGD
Primary source
RGD:3980
See related
Ensembl:ENSRNOG00000008195
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
14-3-3z
Summary
30kDa component of the mitochondrial import stimulation factor, a protein complex that facilitates the import of in vitro synthesized precursor proteins into mitochondria [RGD, Feb 2006]
Expression
Biased expression in Brain (RPKM 1746.4), Adrenal (RPKM 1156.7) and 9 other tissues See more
Orthologs
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Genomic context

See Ywhaz in Genome Data Viewer
Location:
7q22
Exon count:
6
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (67941353..67963651, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (75573553..75598295, complement)

Chromosome 7 - NC_051342.1Genomic Context describing neighboring genes Neighboring gene splicing factor 1-like Neighboring gene poly(A) binding protein, cytoplasmic 1 Neighboring gene Ac1254 Neighboring gene uncharacterized LOC100910524 Neighboring gene zinc finger protein 706

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
ion channel binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein domain specific binding IEA
Inferred from Electronic Annotation
more info
 
protein domain specific binding ISO
Inferred from Sequence Orthology
more info
 
protein domain specific binding ISS
Inferred from Sequence or Structural Similarity
more info
 
protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
protein-containing complex binding IPI
Inferred from Physical Interaction
more info
PubMed 
transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 
ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
Golgi reassembly ISO
Inferred from Sequence Orthology
more info
 
angiogenesis IEA
Inferred from Electronic Annotation
more info
 
angiogenesis ISO
Inferred from Sequence Orthology
more info
 
establishment of Golgi localization ISO
Inferred from Sequence Orthology
more info
 
histamine secretion by mast cell IMP
Inferred from Mutant Phenotype
more info
PubMed 
lung development IEA
Inferred from Electronic Annotation
more info
 
lung development ISO
Inferred from Sequence Orthology
more info
 
protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
protein phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 
protein targeting IEA
Inferred from Electronic Annotation
more info
 
protein targeting ISO
Inferred from Sequence Orthology
more info
 
protein targeting to mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
regulation of ERK1 and ERK2 cascade ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of cell death IEA
Inferred from Electronic Annotation
more info
 
regulation of cell death ISO
Inferred from Sequence Orthology
more info
 
regulation of synapse maturation ISO
Inferred from Sequence Orthology
more info
 
respiratory system process IEA
Inferred from Electronic Annotation
more info
 
respiratory system process ISO
Inferred from Sequence Orthology
more info
 
response to drug IDA
Inferred from Direct Assay
more info
PubMed 
signal transduction ISO
Inferred from Sequence Orthology
more info
 
signal transduction ISS
Inferred from Sequence or Structural Similarity
more info
 
synaptic target recognition IEA
Inferred from Electronic Annotation
more info
 
synaptic target recognition ISO
Inferred from Sequence Orthology
more info
 
tube formation IEA
Inferred from Electronic Annotation
more info
 
tube formation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cell leading edge IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
 
hippocampal mossy fiber to CA3 synapse IEA
Inferred from Electronic Annotation
more info
 
hippocampal mossy fiber to CA3 synapse ISO
Inferred from Sequence Orthology
more info
 
melanosome IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
postsynaptic density IDA
Inferred from Direct Assay
more info
PubMed 
protein-containing complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
14-3-3 protein zeta/delta
Names
KCIP-1
mitochondrial import stimulation factor S1 subunit
protein kinase C inhibitor protein 1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013011.4NP_037143.2  14-3-3 protein zeta/delta

    See identical proteins and their annotated locations for NP_037143.2

    Status: PROVISIONAL

    Source sequence(s)
    JACYVU010000185
    UniProtKB/Swiss-Prot
    P63102
    Related
    ENSRNOP00000030885.4, ENSRNOT00000035628.5
    Conserved Domains (1) summary
    cd10022
    Location:2230
    14-3-3_beta_zeta; 14-3-3 beta and zeta isoforms of 14-3-3 protein

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051342.1 Reference mRatBN7.2 Primary Assembly

    Range
    67941353..67963651 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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