U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LHFPL7 LHFPL tetraspan subfamily member 7 [ Homo sapiens (human) ]

Gene ID: 255349, updated on 26-Oct-2022

Summary

Official Symbol
LHFPL7provided by HGNC
Official Full Name
LHFPL tetraspan subfamily member 7provided by HGNC
Primary source
HGNC:HGNC:33725
See related
Ensembl:ENSG00000206069 AllianceGenome:HGNC:33725
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TMEM211; bA9F11.1
Summary
Predicted to be integral component of membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See LHFPL7 in Genome Data Viewer
Location:
22q11.23
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (24935098..24946694, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (25396656..25408280, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (25331065..25342661, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene piwi like RNA-mediated gene silencing 3 Neighboring gene DNA topoisomerase I pseudogene 2 Neighboring gene small G protein signaling modulator 1 Neighboring gene small nucleolar RNA SNORD56 Neighboring gene KIAA1671 Neighboring gene Sharpr-MPRA regulatory region 10625 Neighboring gene KIAA1671 antisense RNA 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

EBI GWAS Catalog

Description
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
EBI GWAS Catalog

General gene information

Homology

Clone Names

  • MGC163519, MGC163521

Gene Ontology Provided by GOA

Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
LHFPL tetraspan subfamily member 7 protein; transmembrane protein 211

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001663.4NP_001001663.1  LHFPL tetraspan subfamily member 7 protein isoform 1 precursor

    See identical proteins and their annotated locations for NP_001001663.1

    Status: VALIDATED

    Source sequence(s)
    AL050312, BG222046, BU584904
    Consensus CDS
    CCDS33624.1
    UniProtKB/Swiss-Prot
    Q6ICI0
    UniProtKB/TrEMBL
    A0A0C4DG04
    Related
    ENSP00000385494.1, ENST00000407886.1
    Conserved Domains (1) summary
    cl21598
    Location:3996
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
  2. NM_001388199.1NP_001375128.1  LHFPL tetraspan subfamily member 7 protein isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AL050312
    Consensus CDS
    CCDS93134.1
    UniProtKB/Swiss-Prot
    Q6ICI0
    Related
    ENSP00000492160.1, ENST00000640159.2
    Conserved Domains (1) summary
    cl21598
    Location:3167
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    24935098..24946694 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047441305.1XP_047297261.1  transmembrane protein 211 isoform X1

    UniProtKB/Swiss-Prot
    Q6ICI0
    Related
    ENSP00000387813.1, ENST00000423535.1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    25396656..25408280 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)