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EIF2S3B eukaryotic translation initiation factor 2 subunit gamma B [ Homo sapiens (human) ]

Gene ID: 255308, updated on 12-Oct-2019

Summary

Official Symbol
EIF2S3Bprovided by HGNC
Official Full Name
eukaryotic translation initiation factor 2 subunit gamma Bprovided by HGNC
Primary source
HGNC:HGNC:43863
See related
Ensembl:ENSG00000180574
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
eIF2gA; EIF2S3L; eIF-2gA
Orthologs

Genomic context

See EIF2S3B in Genome Data Viewer
Location:
12p13.2
Exon count:
2
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (10505893..10523135)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (10658482..10661126)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene killer cell lectin like receptor C2 Neighboring gene killer cell lectin like receptor C1 Neighboring gene uncharacterized LOC105369657 Neighboring gene uncharacterized LOC105369658 Neighboring gene SLC25A39 pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
GTP binding IEA
Inferred from Electronic Annotation
more info
 
GTPase activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to tRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
translation initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
formation of translation preinitiation complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of translational fidelity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
eukaryotic translation initiation factor 2 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
eukaryotic translation initiation factor 2 subunit 3B
Names
eIF-2-gamma2
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
putative eukaryotic translation initiation factor 2 subunit 3-like protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001357731.1NP_001344660.1  eukaryotic translation initiation factor 2 subunit 3B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC068775, BC087847, DB461648
    Consensus CDS
    CCDS86282.1
    Related
    ENSP00000323063.3, ENST00000322446.3
    Conserved Domains (1) summary
    PTZ00327
    Location:13438
    PTZ00327; eukaryotic translation initiation factor 2 gamma subunit; Provisional
  2. NM_001357734.1NP_001344663.1  eukaryotic translation initiation factor 2 subunit 3B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC068775, BC087847, DB461648, DB527071
    Related
    ENSP00000445077.1, ENST00000538173.1
    Conserved Domains (1) summary
    PTZ00327
    Location:13466
    PTZ00327; eukaryotic translation initiation factor 2 gamma subunit; Provisional

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    10505893..10523135
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_003215.3: Suppressed sequence

    Description
    NG_003215.3: This RefSeq was removed because it is now thought that this gene does encode a protein.
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