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Pax6 paired box 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 25509, updated on 5-Aug-2022

Summary

Official Symbol
Pax6provided by RGD
Official Full Name
paired box 6provided by RGD
Primary source
RGD:3258
See related
Ensembl:ENSRNOG00000004410 AllianceGenome:RGD:3258
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and minor groove of adenine-thymine-rich DNA binding activity. Involved in several processes, including cellular response to hormone stimulus; enteroendocrine cell differentiation; and nervous system development. Located in chromatin and nucleus. Used to study autistic disorder. Biomarker of Smith-Lemli-Opitz syndrome and transient cerebral ischemia. Human ortholog(s) of this gene implicated in bilateral optic nerve hypoplasia; eye disease (multiple); glucose intolerance; and paranoid schizophrenia. Orthologous to human PAX6 (paired box 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 32.2) See more
Orthologs
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Try the new Transcript table

Genomic context

See Pax6 in Genome Data Viewer
Location:
3q33
Exon count:
17
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (92128772..92157022)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (95700241..95728682)

Chromosome 3 - NC_051338.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein LOC691083 Neighboring gene reticulocalbin 1 Neighboring gene elongator acetyltransferase complex subunit 4 Neighboring gene 60S ribosomal protein L35a pseudogene Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC120101618 Neighboring gene inner mitochondrial membrane peptidase subunit 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription activator activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
 
enables DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
enables DNA-binding transcription factor activity TAS
Traceable Author Statement
more info
PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
 
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
 
enables HMG box domain binding IEA
Inferred from Electronic Annotation
more info
 
enables HMG box domain binding ISO
Inferred from Sequence Orthology
more info
 
enables R-SMAD binding IEA
Inferred from Electronic Annotation
more info
 
enables R-SMAD binding ISO
Inferred from Sequence Orthology
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA binding ISO
Inferred from Sequence Orthology
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables RNA polymerase II core promoter sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA polymerase II core promoter sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables chromatin DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables chromatin DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables chromatin binding ISO
Inferred from Sequence Orthology
more info
 
enables co-SMAD binding IEA
Inferred from Electronic Annotation
more info
 
enables co-SMAD binding ISO
Inferred from Sequence Orthology
more info
 
enables double-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables histone acetyltransferase binding IEA
Inferred from Electronic Annotation
more info
 
enables histone acetyltransferase binding ISO
Inferred from Sequence Orthology
more info
 
enables minor groove of adenine-thymine-rich DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein kinase binding IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables transcription cis-regulatory region binding ISO
Inferred from Sequence Orthology
more info
 
enables transcription cis-regulatory region binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables transcription coregulator binding IEA
Inferred from Electronic Annotation
more info
 
enables transcription coregulator binding ISO
Inferred from Sequence Orthology
more info
 
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in DNA demethylation IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA demethylation ISO
Inferred from Sequence Orthology
more info
 
involved_in DNA methylation IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA methylation ISO
Inferred from Sequence Orthology
more info
 
involved_in anatomical structure development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within anterior/posterior pattern specification ISO
Inferred from Sequence Orthology
more info
 
involved_in astrocyte differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in astrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within astrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in astrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within axon guidance ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within axonogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in blood vessel development IEA
Inferred from Electronic Annotation
more info
 
involved_in blood vessel development ISO
Inferred from Sequence Orthology
more info
 
involved_in brain development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within brain development ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within camera-type eye development ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within cell differentiation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within cell fate commitment ISO
Inferred from Sequence Orthology
more info
 
involved_in cell fate determination IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell fate determination ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of cell population proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to fibroblast growth factor stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cellular response to glucose stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cellular response to insulin stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cellular response to leukemia inhibitory factor IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cellular response to leukemia inhibitory factor ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to prostaglandin E stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cellular response to xenobiotic stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in central nervous system development IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cerebellum development IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cerebral cortex development ISO
Inferred from Sequence Orthology
more info
 
involved_in cerebral cortex regionalization IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cerebral cortex regionalization ISO
Inferred from Sequence Orthology
more info
 
involved_in cerebral cortex regionalization ISO
Inferred from Sequence Orthology
more info
 
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
 
involved_in chromatin remodeling ISO
Inferred from Sequence Orthology
more info
 
involved_in commitment of neuronal cell to specific neuron type in forebrain IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within commitment of neuronal cell to specific neuron type in forebrain ISO
Inferred from Sequence Orthology
more info
 
involved_in cornea development in camera-type eye IEA
Inferred from Electronic Annotation
more info
 
involved_in cornea development in camera-type eye ISO
Inferred from Sequence Orthology
more info
 
involved_in dorsal/ventral axis specification IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within dorsal/ventral axis specification ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within dorsal/ventral pattern formation ISO
Inferred from Sequence Orthology
more info
 
involved_in embryonic camera-type eye morphogenesis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within embryonic camera-type eye morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in epithelial cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in establishment of mitotic spindle orientation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within establishment of mitotic spindle orientation ISO
Inferred from Sequence Orthology
more info
 
involved_in eye photoreceptor cell development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within eye photoreceptor cell development ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within forebrain development ISO
Inferred from Sequence Orthology
more info
 
involved_in forebrain dorsal/ventral pattern formation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within forebrain dorsal/ventral pattern formation ISO
Inferred from Sequence Orthology
more info
 
involved_in forebrain-midbrain boundary formation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within forebrain-midbrain boundary formation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within gene expression ISO
Inferred from Sequence Orthology
more info
 
involved_in gene expression ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of glandular epithelial cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 
involved_in glucose homeostasis ISO
Inferred from Sequence Orthology
more info
 
involved_in habenula development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within habenula development ISO
Inferred from Sequence Orthology
more info
 
involved_in hindbrain development IDA
Inferred from Direct Assay
more info
PubMed 
involved_in hindbrain development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in histone acetylation IEA
Inferred from Electronic Annotation
more info
 
involved_in histone acetylation ISO
Inferred from Sequence Orthology
more info
 
involved_in insulin metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in interkinetic nuclear migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in iris morphogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in iris morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in keratinocyte differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within keratinocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in lacrimal gland development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within lacrimal gland development ISO
Inferred from Sequence Orthology
more info
 
involved_in learned vocalization behavior or vocal learning IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in lens development in camera-type eye IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within lens development in camera-type eye ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of epithelial cell proliferation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within negative regulation of epithelial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of neural precursor cell proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of neuroblast proliferation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within negative regulation of neuroblast proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of neuron differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within negative regulation of neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within negative regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in neural crest cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neural precursor cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of neural precursor cell proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in neuroblast proliferation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of neuroblast proliferation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in neuron migration IEA
Inferred from Electronic Annotation
more info
 
involved_in neuron migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within neuron migration ISO
Inferred from Sequence Orthology
more info
 
involved_in neuron migration ISO
Inferred from Sequence Orthology
more info
 
involved_in olfactory bulb development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in olfactory bulb mitral cell layer development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in oligodendrocyte cell fate specification IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within oligodendrocyte cell fate specification ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within pallium development ISO
Inferred from Sequence Orthology
more info
 
involved_in pancreatic A cell development IEA
Inferred from Electronic Annotation
more info
 
involved_in pancreatic A cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in pancreatic A cell development ISO
Inferred from Sequence Orthology
more info
 
involved_in pancreatic A cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in pituitary gland development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within pituitary gland development ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cell fate specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of core promoter binding IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of core promoter binding ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of core promoter binding ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of epithelial cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within positive regulation of epithelial cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of glucagon secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of glutamatergic neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of neuroblast proliferation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within positive regulation of neuroblast proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of neuron migration IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in protein localization to organelle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within protein localization to organelle ISO
Inferred from Sequence Orthology
more info
 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regionalization ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of asymmetric cell division IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of asymmetric cell division ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of neurogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of neurogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of neuron differentiation IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within regulation of neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of neuron projection development IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in regulation of timing of cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of timing of cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in response to ethanol IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to wounding IEA
Inferred from Electronic Annotation
more info
 
involved_in response to wounding ISO
Inferred from Sequence Orthology
more info
 
involved_in retina development in camera-type eye IEA
Inferred from Electronic Annotation
more info
 
involved_in retina development in camera-type eye IEP
Inferred from Expression Pattern
more info
PubMed 
acts_upstream_of_or_within retina development in camera-type eye ISO
Inferred from Sequence Orthology
more info
 
involved_in rhombomere morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in salivary gland morphogenesis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within salivary gland morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in sensory neuron migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in signal transduction involved in regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within signal transduction involved in regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
involved_in smoothened signaling pathway IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within smoothened signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in spinal cord development IEP
Inferred from Expression Pattern
more info
PubMed 
acts_upstream_of_or_within telencephalon regionalization ISO
Inferred from Sequence Orthology
more info
 
involved_in transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in type B pancreatic cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in type B pancreatic cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within type B pancreatic cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in ventral spinal cord development IEA
Inferred from Electronic Annotation
more info
 
involved_in ventral spinal cord development ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in chromatin IDA
Inferred from Direct Assay
more info
PubMed 
located_in chromatin IEA
Inferred from Electronic Annotation
more info
 
located_in chromatin ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
paired box protein Pax-6
Names
oculorhombin
paired box gene 6
paired box homeotic gene 6

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013001.2NP_037133.1  paired box protein Pax-6

    See identical proteins and their annotated locations for NP_037133.1

    Status: PROVISIONAL

    Source sequence(s)
    BC128741
    UniProtKB/Swiss-Prot
    P63016, Q701Q8
    Related
    ENSRNOP00000005882.3, ENSRNOT00000005882.6
    Conserved Domains (2) summary
    smart00351
    Location:4128
    PAX; Paired Box domain
    pfam00046
    Location:214266
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051338.1 Reference mRatBN7.2 Primary Assembly

    Range
    92128772..92157022
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006234636.4XP_006234698.1  paired box protein Pax-6 isoform X1

    See identical proteins and their annotated locations for XP_006234698.1

    UniProtKB/Swiss-Prot
    P63016
    Conserved Domains (2) summary
    smart00351
    Location:4142
    PAX; Paired Box domain
    pfam00046
    Location:228281
    Homeobox; Homeobox domain
  2. XM_006234634.4XP_006234696.1  paired box protein Pax-6 isoform X1

    See identical proteins and their annotated locations for XP_006234696.1

    UniProtKB/Swiss-Prot
    P63016
    Conserved Domains (2) summary
    smart00351
    Location:4142
    PAX; Paired Box domain
    pfam00046
    Location:228281
    Homeobox; Homeobox domain
  3. XM_039104377.1XP_038960305.1  paired box protein Pax-6 isoform X2

    Conserved Domains (2) summary
    smart00351
    Location:4128
    PAX; Paired Box domain
    pfam00046
    Location:214267
    Homeobox; Homeobox domain
  4. XM_006234633.4XP_006234695.1  paired box protein Pax-6 isoform X1

    See identical proteins and their annotated locations for XP_006234695.1

    UniProtKB/Swiss-Prot
    P63016
    Conserved Domains (2) summary
    smart00351
    Location:4142
    PAX; Paired Box domain
    pfam00046
    Location:228281
    Homeobox; Homeobox domain
  5. XM_006234635.4XP_006234697.1  paired box protein Pax-6 isoform X1

    See identical proteins and their annotated locations for XP_006234697.1

    UniProtKB/Swiss-Prot
    P63016
    Related
    ENSRNOP00000071013.2, ENSRNOT00000089525.2
    Conserved Domains (2) summary
    smart00351
    Location:4142
    PAX; Paired Box domain
    pfam00046
    Location:228281
    Homeobox; Homeobox domain
  6. XM_039104376.1XP_038960304.1  paired box protein Pax-6 isoform X1

    Conserved Domains (2) summary
    smart00351
    Location:4142
    PAX; Paired Box domain
    pfam00046
    Location:228281
    Homeobox; Homeobox domain